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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CACNA1A
All Species:
5.45
Human Site:
S429
Identified Species:
12
UniProt:
O00555
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00555
NP_001120693.1
2505
282365
S429
R
R
T
T
I
K
K
S
K
T
D
L
L
N
P
Chimpanzee
Pan troglodytes
XP_520396
2784
310342
K870
I
P
R
A
W
E
K
K
K
K
K
D
L
D
H
Rhesus Macaque
Macaca mulatta
XP_001110352
2383
269535
T420
A
T
I
K
R
S
R
T
E
A
M
T
R
D
S
Dog
Lupus familis
XP_537779
2046
229120
I199
I
L
T
V
F
Q
C
I
T
M
E
G
W
T
D
Cat
Felis silvestris
Mouse
Mus musculus
P97445
2368
267629
S431
R
R
A
T
L
K
K
S
K
T
D
L
L
N
P
Rat
Rattus norvegicus
P54282
2212
251509
F365
L
G
V
L
S
G
E
F
A
K
E
R
E
R
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
O73700
2190
249326
D343
N
G
G
I
T
N
F
D
N
F
A
F
A
M
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_690548
2303
262065
R414
P
F
D
G
S
R
R
R
P
T
I
K
K
S
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91645
1851
212452
Honey Bee
Apis mellifera
NP_001159376
1904
215872
R57
Q
R
Y
A
G
R
R
R
R
A
V
T
T
S
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001186699
1966
222605
A119
Y
L
Q
D
E
E
K
A
A
E
D
D
G
S
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
55
55.9
54.6
N.A.
87.9
82.7
N.A.
N.A.
35.9
N.A.
72.3
N.A.
43
44.4
N.A.
39.6
Protein Similarity:
100
63.5
66.3
63.4
N.A.
89.9
84.6
N.A.
N.A.
50.4
N.A.
80
N.A.
53.9
55.4
N.A.
51.6
P-Site Identity:
100
20
0
6.6
N.A.
86.6
0
N.A.
N.A.
0
N.A.
6.6
N.A.
0
6.6
N.A.
13.3
P-Site Similarity:
100
33.3
26.6
20
N.A.
93.3
13.3
N.A.
N.A.
0
N.A.
26.6
N.A.
0
40
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
10
19
0
0
0
10
19
19
10
0
10
0
0
% A
% Cys:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
10
0
0
0
10
0
0
28
19
0
19
19
% D
% Glu:
0
0
0
0
10
19
10
0
10
10
19
0
10
0
10
% E
% Phe:
0
10
0
0
10
0
10
10
0
10
0
10
0
0
0
% F
% Gly:
0
19
10
10
10
10
0
0
0
0
0
10
10
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% H
% Ile:
19
0
10
10
10
0
0
10
0
0
10
0
0
0
0
% I
% Lys:
0
0
0
10
0
19
37
10
28
19
10
10
10
0
10
% K
% Leu:
10
19
0
10
10
0
0
0
0
0
0
19
28
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
10
10
0
0
10
0
% M
% Asn:
10
0
0
0
0
10
0
0
10
0
0
0
0
19
0
% N
% Pro:
10
10
0
0
0
0
0
0
10
0
0
0
0
0
19
% P
% Gln:
10
0
10
0
0
10
0
0
0
0
0
0
0
0
0
% Q
% Arg:
19
28
10
0
10
19
28
19
10
0
0
10
10
10
0
% R
% Ser:
0
0
0
0
19
10
0
19
0
0
0
0
0
28
10
% S
% Thr:
0
10
19
19
10
0
0
10
10
28
0
19
10
10
0
% T
% Val:
0
0
10
10
0
0
0
0
0
0
10
0
0
0
10
% V
% Trp:
0
0
0
0
10
0
0
0
0
0
0
0
10
0
0
% W
% Tyr:
10
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _