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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PES1
All Species:
22.73
Human Site:
T515
Identified Species:
35.71
UniProt:
O00541
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.21
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00541
NP_055118.1
588
68003
T515
K
P
R
V
M
A
G
T
L
K
L
E
D
K
Q
Chimpanzee
Pan troglodytes
XP_001143647
588
67990
T515
K
P
R
V
M
A
G
T
L
K
L
E
D
K
Q
Rhesus Macaque
Macaca mulatta
XP_001110399
679
77752
T606
K
P
R
V
M
A
G
T
L
K
L
E
D
K
Q
Dog
Lupus familis
XP_543480
584
67748
T511
K
P
R
V
M
A
G
T
V
K
L
Q
D
K
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9EQ61
584
67777
T511
K
P
Q
V
M
A
G
T
V
K
L
E
D
K
Q
Rat
Rattus norvegicus
Q3B8N8
586
67586
T513
K
P
Q
V
M
A
G
T
V
K
L
E
D
R
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508188
378
43758
L324
E
E
S
E
A
K
R
L
A
I
M
M
M
K
K
Chicken
Gallus gallus
XP_001234133
524
60851
E466
L
E
Q
E
Q
Q
S
E
E
K
R
L
A
I
M
Frog
Xenopus laevis
Q7ZY69
574
67098
K502
N
V
K
V
T
A
G
K
V
K
V
E
D
R
T
Zebra Danio
Brachydanio rerio
P79741
583
67880
K511
S
V
K
V
T
P
G
K
A
K
A
E
N
R
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VL96
627
73844
K540
K
M
S
V
Q
S
G
K
V
H
K
V
N
K
R
Honey Bee
Apis mellifera
XP_001119862
555
66223
R489
E
D
P
W
E
K
K
R
Q
E
R
Q
E
Y
R
Nematode Worm
Caenorhab. elegans
Q95Y89
531
61607
A465
K
P
K
G
I
H
I
A
V
G
Q
M
H
K
K
Sea Urchin
Strong. purpuratus
XP_001200338
596
69851
E523
N
L
S
V
A
E
G
E
V
E
K
V
N
P
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SFC2
663
75275
K594
Q
N
T
K
V
D
S
K
T
K
A
K
L
E
Q
Conservation
Percent
Protein Identity:
100
99.3
83
90.3
N.A.
89.4
89.4
N.A.
47.4
72.6
71.4
73.9
N.A.
43.2
46
42.6
49.6
Protein Similarity:
100
99.4
85.1
94.3
N.A.
93.8
94
N.A.
55.6
80.2
86.2
84
N.A.
60.7
62.5
58.5
66.6
P-Site Identity:
100
100
100
86.6
N.A.
86.6
80
N.A.
6.6
6.6
40
26.6
N.A.
26.6
0
20
13.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
26.6
13.3
66.6
46.6
N.A.
53.3
33.3
46.6
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
40.1
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
55.6
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
14
47
0
7
14
0
14
0
7
0
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
7
0
0
0
7
0
0
0
0
0
0
47
0
0
% D
% Glu:
14
14
0
14
7
7
0
14
7
14
0
47
7
7
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
7
0
0
67
0
0
7
0
0
0
0
0
% G
% His:
0
0
0
0
0
7
0
0
0
7
0
0
7
0
0
% H
% Ile:
0
0
0
0
7
0
7
0
0
7
0
0
0
7
0
% I
% Lys:
54
0
20
7
0
14
7
27
0
67
14
7
0
54
14
% K
% Leu:
7
7
0
0
0
0
0
7
20
0
40
7
7
0
0
% L
% Met:
0
7
0
0
40
0
0
0
0
0
7
14
7
0
7
% M
% Asn:
14
7
0
0
0
0
0
0
0
0
0
0
20
0
0
% N
% Pro:
0
47
7
0
0
7
0
0
0
0
0
0
0
7
0
% P
% Gln:
7
0
20
0
14
7
0
0
7
0
7
14
0
0
47
% Q
% Arg:
0
0
27
0
0
0
7
7
0
0
14
0
0
20
14
% R
% Ser:
7
0
20
0
0
7
14
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
7
0
14
0
0
40
7
0
0
0
0
0
14
% T
% Val:
0
14
0
67
7
0
0
0
47
0
7
14
0
0
0
% V
% Trp:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _