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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PES1
All Species:
21.82
Human Site:
S578
Identified Species:
34.29
UniProt:
O00541
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00541
NP_055118.1
588
68003
S578
A
H
D
E
A
V
R
S
E
K
K
A
K
K
A
Chimpanzee
Pan troglodytes
XP_001143647
588
67990
S578
A
H
D
E
A
V
R
S
E
K
K
A
K
K
A
Rhesus Macaque
Macaca mulatta
XP_001110399
679
77752
S669
A
H
D
E
A
M
R
S
E
K
K
A
K
K
A
Dog
Lupus familis
XP_543480
584
67748
S574
A
H
D
E
A
V
R
S
Q
K
K
A
K
K
I
Cat
Felis silvestris
Mouse
Mus musculus
Q9EQ61
584
67777
S574
A
H
D
D
A
V
R
S
E
K
K
A
K
R
T
Rat
Rattus norvegicus
Q3B8N8
586
67586
S576
A
H
D
D
A
V
R
S
E
K
K
A
K
R
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508188
378
43758
K371
A
K
K
S
E
K
K
K
S
K
K
A
R
R
E
Chicken
Gallus gallus
XP_001234133
524
60851
E513
A
H
D
T
A
L
K
E
E
K
K
K
T
K
K
Frog
Xenopus laevis
Q7ZY69
574
67098
V565
A
H
D
E
A
V
K
V
E
R
K
K
K
A
K
Zebra Danio
Brachydanio rerio
P79741
583
67880
A574
A
H
D
D
A
S
K
A
D
K
K
K
K
K
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VL96
627
73844
A607
E
K
E
A
R
K
T
A
K
R
E
A
R
K
E
Honey Bee
Apis mellifera
XP_001119862
555
66223
Q540
L
H
D
T
A
E
K
Q
K
R
K
E
E
R
K
Nematode Worm
Caenorhab. elegans
Q95Y89
531
61607
L519
N
R
N
D
A
L
K
L
K
K
K
A
K
L
A
Sea Urchin
Strong. purpuratus
XP_001200338
596
69851
V586
K
Y
D
E
E
Q
K
V
N
K
K
K
K
K
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SFC2
663
75275
A650
A
Q
D
E
K
L
R
A
K
R
R
K
L
E
K
Conservation
Percent
Protein Identity:
100
99.3
83
90.3
N.A.
89.4
89.4
N.A.
47.4
72.6
71.4
73.9
N.A.
43.2
46
42.6
49.6
Protein Similarity:
100
99.4
85.1
94.3
N.A.
93.8
94
N.A.
55.6
80.2
86.2
84
N.A.
60.7
62.5
58.5
66.6
P-Site Identity:
100
100
93.3
86.6
N.A.
80
80
N.A.
26.6
53.3
60
53.3
N.A.
13.3
26.6
40
40
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
46.6
66.6
73.3
80
N.A.
53.3
60
73.3
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
40.1
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
55.6
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
26.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
66.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
74
0
0
7
74
0
0
20
0
0
0
60
0
7
27
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
80
27
0
0
0
0
7
0
0
0
0
0
0
% D
% Glu:
7
0
7
47
14
7
0
7
47
0
7
7
7
7
14
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
67
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% I
% Lys:
7
14
7
0
7
14
47
7
27
74
87
34
67
54
34
% K
% Leu:
7
0
0
0
0
20
0
7
0
0
0
0
7
7
0
% L
% Met:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% M
% Asn:
7
0
7
0
0
0
0
0
7
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
7
0
0
0
7
0
7
7
0
0
0
0
0
0
% Q
% Arg:
0
7
0
0
7
0
47
0
0
27
7
0
14
27
0
% R
% Ser:
0
0
0
7
0
7
0
40
7
0
0
0
0
0
0
% S
% Thr:
0
0
0
14
0
0
7
0
0
0
0
0
7
0
14
% T
% Val:
0
0
0
0
0
40
0
14
0
0
0
0
0
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _