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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LAD1 All Species: 9.09
Human Site: S251 Identified Species: 33.33
UniProt: O00515 Number Species: 6
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O00515 NP_005549.2 517 57131 S251 A P G M A L G S G R R L V S E
Chimpanzee Pan troglodytes XP_001146774 517 57161 S251 A P G M A L G S G R R L V S E
Rhesus Macaque Macaca mulatta XP_001108686 516 56913 S250 A P G M A L G S G R R L V S E
Dog Lupus familis XP_849490 477 51627 R212 E K R P L L E R T G V P E K P
Cat Felis silvestris
Mouse Mus musculus P57016 528 58846 V262 P E R R S P P V L E K A I V S
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517359 362 40602 P97 S V L K L S P P P S P D Q D E
Chicken Gallus gallus P12957 771 88729 E480 E Q K A Q N G E R E L T T P K
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.6 94.3 51.2 N.A. 63.8 N.A. N.A. 26.5 22 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99 96.7 63 N.A. 75.5 N.A. N.A. 43.9 37.6 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 6.6 N.A. 0 N.A. N.A. 6.6 6.6 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 6.6 N.A. 20 N.A. N.A. 13.3 13.3 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 43 0 0 15 43 0 0 0 0 0 0 15 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 15 0 15 0 % D
% Glu: 29 15 0 0 0 0 15 15 0 29 0 0 15 0 58 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 43 0 0 0 58 0 43 15 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 15 0 0 % I
% Lys: 0 15 15 15 0 0 0 0 0 0 15 0 0 15 15 % K
% Leu: 0 0 15 0 29 58 0 0 15 0 15 43 0 0 0 % L
% Met: 0 0 0 43 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 15 0 0 0 0 0 0 0 0 0 % N
% Pro: 15 43 0 15 0 15 29 15 15 0 15 15 0 15 15 % P
% Gln: 0 15 0 0 15 0 0 0 0 0 0 0 15 0 0 % Q
% Arg: 0 0 29 15 0 0 0 15 15 43 43 0 0 0 0 % R
% Ser: 15 0 0 0 15 15 0 43 0 15 0 0 0 43 15 % S
% Thr: 0 0 0 0 0 0 0 0 15 0 0 15 15 0 0 % T
% Val: 0 15 0 0 0 0 0 15 0 0 15 0 43 15 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _