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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EXOC5
All Species:
26.67
Human Site:
Y621
Identified Species:
45.13
UniProt:
O00471
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00471
NP_006535.1
708
81853
Y621
I
Y
E
H
L
Q
Q
Y
S
Y
S
C
M
G
G
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001090127
708
81848
Y621
I
Y
E
H
L
Q
Q
Y
S
Y
S
C
M
G
G
Dog
Lupus familis
XP_547832
708
81807
Y621
I
Y
E
H
L
Q
Q
Y
S
Y
S
C
M
G
G
Cat
Felis silvestris
Mouse
Mus musculus
Q3TPX4
708
81777
Y621
I
Y
E
H
L
Q
Q
Y
S
Y
S
C
M
G
D
Rat
Rattus norvegicus
P97878
708
81718
Y621
T
Y
E
H
L
Q
Q
Y
S
Y
S
C
M
G
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511952
708
81659
Y621
I
Y
E
H
L
Q
Q
Y
S
Y
S
C
M
G
G
Chicken
Gallus gallus
NP_001012607
707
81709
Y620
I
Y
E
H
L
Q
Q
Y
S
Y
S
C
M
G
G
Frog
Xenopus laevis
NP_001085732
708
81822
F621
I
Y
E
H
L
Q
Q
F
S
Y
S
S
M
G
G
Zebra Danio
Brachydanio rerio
NP_001107268
708
81758
F621
I
H
E
H
L
Q
Q
F
S
Y
S
S
M
G
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9XTM1
710
82012
M619
I
Y
D
H
L
Q
T
M
Q
F
N
T
A
G
A
Honey Bee
Apis mellifera
XP_624953
716
82975
F625
I
Y
D
H
L
Q
Q
F
Q
F
N
S
A
G
A
Nematode Worm
Caenorhab. elegans
Q18406
659
75732
F574
M
L
T
H
I
Q
Q
F
T
Y
N
S
T
G
A
Sea Urchin
Strong. purpuratus
XP_784056
728
83314
F638
V
Y
D
H
L
Q
Q
F
T
Y
N
S
M
G
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8RVQ5
825
89676
F734
L
L
T
H
W
Q
K
F
T
F
N
P
S
G
G
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.8
99.4
N.A.
98.3
98.1
N.A.
96.7
95.4
89.8
83.3
N.A.
43.3
47.4
34.1
48.4
Protein Similarity:
100
N.A.
99.8
99.7
N.A.
99.1
99.2
N.A.
98.7
98.1
95.7
93.2
N.A.
65.3
70.5
56.5
69.6
P-Site Identity:
100
N.A.
100
100
N.A.
93.3
93.3
N.A.
100
100
86.6
80
N.A.
40
46.6
33.3
53.3
P-Site Similarity:
100
N.A.
100
100
N.A.
93.3
93.3
N.A.
100
100
93.3
93.3
N.A.
60
73.3
66.6
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.1
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
41
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
66.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
15
0
29
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
50
0
0
0
% C
% Asp:
0
0
22
0
0
0
0
0
0
0
0
0
0
0
8
% D
% Glu:
0
0
65
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
43
0
22
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
100
65
% G
% His:
0
8
0
100
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
72
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% K
% Leu:
8
15
0
0
86
0
0
0
0
0
0
0
0
0
0
% L
% Met:
8
0
0
0
0
0
0
8
0
0
0
0
72
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
36
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% P
% Gln:
0
0
0
0
0
100
86
0
15
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
65
0
65
36
8
0
0
% S
% Thr:
8
0
15
0
0
0
8
0
22
0
0
8
8
0
0
% T
% Val:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
79
0
0
0
0
0
50
0
79
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _