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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EXOC5
All Species:
36.67
Human Site:
Y481
Identified Species:
62.05
UniProt:
O00471
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00471
NP_006535.1
708
81853
Y481
D
S
R
N
A
N
L
Y
F
L
D
V
V
Q
Q
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001090127
708
81848
Y481
D
S
R
N
A
N
L
Y
F
L
D
V
V
Q
Q
Dog
Lupus familis
XP_547832
708
81807
Y481
D
S
R
N
A
N
L
Y
F
L
D
V
V
Q
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q3TPX4
708
81777
Y481
D
S
R
N
A
N
L
Y
F
L
D
V
V
Q
Q
Rat
Rattus norvegicus
P97878
708
81718
Y481
D
S
R
N
A
N
L
Y
F
L
D
V
V
Q
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511952
708
81659
Y481
D
S
R
T
A
N
L
Y
F
L
D
V
V
Q
Q
Chicken
Gallus gallus
NP_001012607
707
81709
Y480
D
S
K
N
A
N
L
Y
F
L
D
V
V
H
Q
Frog
Xenopus laevis
NP_001085732
708
81822
Y481
D
S
K
N
A
N
L
Y
F
F
D
V
V
H
Q
Zebra Danio
Brachydanio rerio
NP_001107268
708
81758
Y481
D
A
K
N
A
N
L
Y
F
L
D
V
V
Q
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9XTM1
710
82012
L480
E
G
R
V
F
P
Q
L
Y
F
F
D
V
V
Q
Honey Bee
Apis mellifera
XP_624953
716
82975
I486
E
S
R
T
Q
P
E
I
H
F
F
N
I
V
R
Nematode Worm
Caenorhab. elegans
Q18406
659
75732
A435
E
S
K
T
E
P
P
A
Y
F
F
S
V
V
A
Sea Urchin
Strong. purpuratus
XP_784056
728
83314
S497
E
P
R
S
P
P
A
S
Y
F
F
E
I
V
C
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8RVQ5
825
89676
R562
L
S
E
A
A
A
L
R
E
R
F
V
L
G
R
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.8
99.4
N.A.
98.3
98.1
N.A.
96.7
95.4
89.8
83.3
N.A.
43.3
47.4
34.1
48.4
Protein Similarity:
100
N.A.
99.8
99.7
N.A.
99.1
99.2
N.A.
98.7
98.1
95.7
93.2
N.A.
65.3
70.5
56.5
69.6
P-Site Identity:
100
N.A.
100
100
N.A.
100
100
N.A.
93.3
86.6
80
86.6
N.A.
20
13.3
13.3
6.6
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
93.3
93.3
86.6
100
N.A.
33.3
33.3
33.3
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.1
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
41
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
8
72
8
8
8
0
0
0
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% C
% Asp:
65
0
0
0
0
0
0
0
0
0
65
8
0
0
0
% D
% Glu:
29
0
8
0
8
0
8
0
8
0
0
8
0
0
0
% E
% Phe:
0
0
0
0
8
0
0
0
65
36
36
0
0
0
0
% F
% Gly:
0
8
0
0
0
0
0
0
0
0
0
0
0
8
0
% G
% His:
0
0
0
0
0
0
0
0
8
0
0
0
0
15
0
% H
% Ile:
0
0
0
0
0
0
0
8
0
0
0
0
15
0
0
% I
% Lys:
0
0
29
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
8
0
0
0
0
0
72
8
0
58
0
0
8
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
58
0
65
0
0
0
0
0
8
0
0
0
% N
% Pro:
0
8
0
0
8
29
8
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
8
0
8
0
0
0
0
0
0
50
72
% Q
% Arg:
0
0
65
0
0
0
0
8
0
8
0
0
0
0
15
% R
% Ser:
0
79
0
8
0
0
0
8
0
0
0
8
0
0
0
% S
% Thr:
0
0
0
22
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
8
0
0
0
0
0
0
0
72
79
29
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
65
22
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _