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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EXOC5
All Species:
45.15
Human Site:
Y105
Identified Species:
76.41
UniProt:
O00471
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00471
NP_006535.1
708
81853
Y105
E
L
D
E
H
I
S
Y
V
A
T
K
V
C
H
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001090127
708
81848
Y105
E
L
D
E
H
I
S
Y
V
A
T
K
V
C
H
Dog
Lupus familis
XP_547832
708
81807
Y105
E
L
D
E
H
I
S
Y
V
A
T
K
V
C
H
Cat
Felis silvestris
Mouse
Mus musculus
Q3TPX4
708
81777
Y105
E
L
D
E
H
I
S
Y
V
A
T
K
V
C
H
Rat
Rattus norvegicus
P97878
708
81718
Y105
E
L
D
E
H
I
S
Y
V
A
T
K
V
C
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511952
708
81659
Y105
E
L
D
E
H
I
S
Y
V
A
T
K
V
C
H
Chicken
Gallus gallus
NP_001012607
707
81709
Y104
E
L
D
E
H
I
S
Y
V
A
T
K
V
C
H
Frog
Xenopus laevis
NP_001085732
708
81822
Y105
E
L
D
E
H
I
S
Y
V
A
T
K
V
C
H
Zebra Danio
Brachydanio rerio
NP_001107268
708
81758
Y105
E
L
D
E
H
I
S
Y
V
A
T
K
V
C
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9XTM1
710
82012
S105
Q
L
D
E
K
I
N
S
V
A
G
K
I
M
H
Honey Bee
Apis mellifera
XP_624953
716
82975
L108
Q
L
D
E
R
I
N
L
V
A
T
K
V
L
H
Nematode Worm
Caenorhab. elegans
Q18406
659
75732
A62
Q
L
D
H
T
M
Q
A
V
S
T
K
V
V
H
Sea Urchin
Strong. purpuratus
XP_784056
728
83314
S119
E
L
D
E
R
I
N
S
V
A
T
K
V
V
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8RVQ5
825
89676
S169
K
I
G
D
H
L
Q
S
A
D
A
Q
R
E
T
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.8
99.4
N.A.
98.3
98.1
N.A.
96.7
95.4
89.8
83.3
N.A.
43.3
47.4
34.1
48.4
Protein Similarity:
100
N.A.
99.8
99.7
N.A.
99.1
99.2
N.A.
98.7
98.1
95.7
93.2
N.A.
65.3
70.5
56.5
69.6
P-Site Identity:
100
N.A.
100
100
N.A.
100
100
N.A.
100
100
100
100
N.A.
53.3
66.6
46.6
73.3
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
100
100
100
100
N.A.
73.3
80
66.6
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.1
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
41
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
8
8
86
8
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
65
0
% C
% Asp:
0
0
93
8
0
0
0
0
0
8
0
0
0
0
0
% D
% Glu:
72
0
0
86
0
0
0
0
0
0
0
0
0
8
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
8
0
0
0
0
0
0
0
8
0
0
0
0
% G
% His:
0
0
0
8
72
0
0
0
0
0
0
0
0
0
93
% H
% Ile:
0
8
0
0
0
86
0
0
0
0
0
0
8
0
0
% I
% Lys:
8
0
0
0
8
0
0
0
0
0
0
93
0
0
0
% K
% Leu:
0
93
0
0
0
8
0
8
0
0
0
0
0
8
0
% L
% Met:
0
0
0
0
0
8
0
0
0
0
0
0
0
8
0
% M
% Asn:
0
0
0
0
0
0
22
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
22
0
0
0
0
0
15
0
0
0
0
8
0
0
0
% Q
% Arg:
0
0
0
0
15
0
0
0
0
0
0
0
8
0
0
% R
% Ser:
0
0
0
0
0
0
65
22
0
8
0
0
0
0
0
% S
% Thr:
0
0
0
0
8
0
0
0
0
0
86
0
0
0
8
% T
% Val:
0
0
0
0
0
0
0
0
93
0
0
0
86
15
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
65
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _