KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EXOC5
All Species:
45.45
Human Site:
T405
Identified Species:
76.92
UniProt:
O00471
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00471
NP_006535.1
708
81853
T405
P
L
G
P
S
I
D
T
H
G
E
T
F
L
S
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001090127
708
81848
T405
P
L
G
P
S
I
D
T
H
G
E
T
F
L
S
Dog
Lupus familis
XP_547832
708
81807
T405
P
L
G
P
S
I
D
T
H
G
E
T
F
L
S
Cat
Felis silvestris
Mouse
Mus musculus
Q3TPX4
708
81777
T405
P
L
G
P
S
I
D
T
H
G
E
T
F
L
S
Rat
Rattus norvegicus
P97878
708
81718
T405
P
L
G
P
S
I
D
T
H
G
E
T
F
L
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511952
708
81659
T405
P
L
G
P
S
I
D
T
H
G
E
T
F
L
S
Chicken
Gallus gallus
NP_001012607
707
81709
T404
P
L
G
P
S
I
D
T
H
G
E
T
F
L
S
Frog
Xenopus laevis
NP_001085732
708
81822
T405
P
L
G
P
S
I
D
T
H
G
E
T
F
L
S
Zebra Danio
Brachydanio rerio
NP_001107268
708
81758
T405
P
L
G
P
S
I
D
T
H
G
E
T
L
L
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9XTM1
710
82012
Y404
N
I
A
A
I
E
D
Y
G
G
E
T
F
L
S
Honey Bee
Apis mellifera
XP_624953
716
82975
Y410
N
I
A
Q
I
E
N
Y
G
G
E
T
F
L
S
Nematode Worm
Caenorhab. elegans
Q18406
659
75732
Y359
R
L
M
N
V
E
T
Y
G
G
E
T
F
V
A
Sea Urchin
Strong. purpuratus
XP_784056
728
83314
Y421
G
A
A
P
V
A
D
Y
K
G
E
T
F
L
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8RVQ5
825
89676
G486
G
T
I
G
R
S
K
G
A
S
I
S
S
S
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.8
99.4
N.A.
98.3
98.1
N.A.
96.7
95.4
89.8
83.3
N.A.
43.3
47.4
34.1
48.4
Protein Similarity:
100
N.A.
99.8
99.7
N.A.
99.1
99.2
N.A.
98.7
98.1
95.7
93.2
N.A.
65.3
70.5
56.5
69.6
P-Site Identity:
100
N.A.
100
100
N.A.
100
100
N.A.
100
100
100
93.3
N.A.
46.6
40
33.3
53.3
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
100
100
100
93.3
N.A.
53.3
53.3
46.6
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.1
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
41
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
22
8
0
8
0
0
8
0
0
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
79
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
22
0
0
0
0
93
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
86
0
0
% F
% Gly:
15
0
65
8
0
0
0
8
22
93
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
65
0
0
0
0
0
0
% H
% Ile:
0
15
8
0
15
65
0
0
0
0
8
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
8
0
8
0
0
0
0
0
0
% K
% Leu:
0
72
0
0
0
0
0
0
0
0
0
0
8
86
8
% L
% Met:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
15
0
0
8
0
0
8
0
0
0
0
0
0
0
0
% N
% Pro:
65
0
0
72
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
8
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
65
8
0
0
0
8
0
8
8
8
86
% S
% Thr:
0
8
0
0
0
0
8
65
0
0
0
93
0
0
0
% T
% Val:
0
0
0
0
15
0
0
0
0
0
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
29
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _