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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EXOC5
All Species:
36.67
Human Site:
T312
Identified Species:
62.05
UniProt:
O00471
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00471
NP_006535.1
708
81853
T312
K
N
L
Y
D
L
Y
T
R
T
T
N
L
S
S
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001090127
708
81848
T312
K
N
L
Y
D
L
Y
T
R
T
T
N
L
S
S
Dog
Lupus familis
XP_547832
708
81807
T312
K
N
L
Y
D
L
Y
T
R
T
T
N
L
S
S
Cat
Felis silvestris
Mouse
Mus musculus
Q3TPX4
708
81777
T312
K
S
L
Y
D
L
Y
T
R
T
T
G
L
S
S
Rat
Rattus norvegicus
P97878
708
81718
T312
K
S
L
Y
D
L
Y
T
R
T
T
S
L
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511952
708
81659
T312
K
N
L
Y
D
L
Y
T
R
T
T
N
L
S
S
Chicken
Gallus gallus
NP_001012607
707
81709
T311
K
N
L
Y
D
L
Y
T
R
T
T
N
L
S
S
Frog
Xenopus laevis
NP_001085732
708
81822
T312
K
S
L
Y
D
L
Y
T
R
T
T
G
L
S
S
Zebra Danio
Brachydanio rerio
NP_001107268
708
81758
T312
K
N
L
Y
D
L
Y
T
R
T
T
A
L
A
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9XTM1
710
82012
Y311
L
R
T
L
Y
E
L
Y
S
R
T
L
K
L
S
Honey Bee
Apis mellifera
XP_624953
716
82975
V317
Y
D
L
Y
T
R
T
V
K
L
S
T
E
L
K
Nematode Worm
Caenorhab. elegans
Q18406
659
75732
D266
D
Q
E
H
Y
L
R
D
L
A
Y
L
Y
S
S
Sea Urchin
Strong. purpuratus
XP_784056
728
83314
D328
Q
H
L
Y
V
R
T
D
R
L
T
S
A
I
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8RVQ5
825
89676
S393
L
A
K
P
S
L
M
S
P
P
P
V
Q
E
G
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.8
99.4
N.A.
98.3
98.1
N.A.
96.7
95.4
89.8
83.3
N.A.
43.3
47.4
34.1
48.4
Protein Similarity:
100
N.A.
99.8
99.7
N.A.
99.1
99.2
N.A.
98.7
98.1
95.7
93.2
N.A.
65.3
70.5
56.5
69.6
P-Site Identity:
100
N.A.
100
100
N.A.
86.6
86.6
N.A.
100
100
86.6
80
N.A.
13.3
13.3
20
26.6
P-Site Similarity:
100
N.A.
100
100
N.A.
93.3
100
N.A.
100
100
93.3
93.3
N.A.
13.3
33.3
26.6
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.1
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
41
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
0
0
0
0
8
0
8
8
8
15
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
8
0
0
65
0
0
15
0
0
0
0
0
0
0
% D
% Glu:
0
0
8
0
0
8
0
0
0
0
0
0
8
8
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
15
0
0
8
% G
% His:
0
8
0
8
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% I
% Lys:
65
0
8
0
0
0
0
0
8
0
0
0
8
0
8
% K
% Leu:
15
0
79
8
0
79
8
0
8
15
0
15
65
15
0
% L
% Met:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% M
% Asn:
0
43
0
0
0
0
0
0
0
0
0
36
0
0
0
% N
% Pro:
0
0
0
8
0
0
0
0
8
8
8
0
0
0
0
% P
% Gln:
8
8
0
0
0
0
0
0
0
0
0
0
8
0
0
% Q
% Arg:
0
8
0
0
0
15
8
0
72
8
0
0
0
0
0
% R
% Ser:
0
22
0
0
8
0
0
8
8
0
8
15
0
65
72
% S
% Thr:
0
0
8
0
8
0
15
65
0
65
79
8
0
0
0
% T
% Val:
0
0
0
0
8
0
0
8
0
0
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
79
15
0
65
8
0
0
8
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _