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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EXOC5
All Species:
28.79
Human Site:
S473
Identified Species:
48.72
UniProt:
O00471
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00471
NP_006535.1
708
81853
S473
G
L
A
G
I
P
S
S
D
S
R
N
A
N
L
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001090127
708
81848
S473
G
L
A
G
I
P
S
S
D
S
R
N
A
N
L
Dog
Lupus familis
XP_547832
708
81807
S473
G
L
A
G
I
P
S
S
D
S
R
N
A
N
L
Cat
Felis silvestris
Mouse
Mus musculus
Q3TPX4
708
81777
S473
G
L
A
G
I
P
S
S
D
S
R
N
A
N
L
Rat
Rattus norvegicus
P97878
708
81718
S473
G
L
A
G
I
P
S
S
D
S
R
N
A
N
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511952
708
81659
S473
G
L
A
G
I
P
S
S
D
S
R
T
A
N
L
Chicken
Gallus gallus
NP_001012607
707
81709
S472
G
L
A
G
I
P
S
S
D
S
K
N
A
N
L
Frog
Xenopus laevis
NP_001085732
708
81822
P473
G
L
V
A
I
P
S
P
D
S
K
N
A
N
L
Zebra Danio
Brachydanio rerio
NP_001107268
708
81758
A473
G
L
S
A
I
P
S
A
D
A
K
N
A
N
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9XTM1
710
82012
A472
G
L
Q
A
V
P
L
A
E
G
R
V
F
P
Q
Honey Bee
Apis mellifera
XP_624953
716
82975
P478
G
L
Q
S
V
P
I
P
E
S
R
T
Q
P
E
Nematode Worm
Caenorhab. elegans
Q18406
659
75732
A427
G
L
A
G
I
S
L
A
E
S
K
T
E
P
P
Sea Urchin
Strong. purpuratus
XP_784056
728
83314
G489
G
L
T
G
I
P
M
G
E
P
R
S
P
P
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8RVQ5
825
89676
S554
G
L
E
R
A
R
D
S
L
S
E
A
A
A
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.8
99.4
N.A.
98.3
98.1
N.A.
96.7
95.4
89.8
83.3
N.A.
43.3
47.4
34.1
48.4
Protein Similarity:
100
N.A.
99.8
99.7
N.A.
99.1
99.2
N.A.
98.7
98.1
95.7
93.2
N.A.
65.3
70.5
56.5
69.6
P-Site Identity:
100
N.A.
100
100
N.A.
100
100
N.A.
93.3
93.3
73.3
66.6
N.A.
26.6
33.3
40
40
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
93.3
100
80
93.3
N.A.
46.6
46.6
60
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.1
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
41
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
58
22
8
0
0
22
0
8
0
8
72
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
8
0
65
0
0
0
0
0
0
% D
% Glu:
0
0
8
0
0
0
0
0
29
0
8
0
8
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% F
% Gly:
100
0
0
65
0
0
0
8
0
8
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
79
0
8
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
29
0
0
0
0
% K
% Leu:
0
100
0
0
0
0
15
0
8
0
0
0
0
0
72
% L
% Met:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
58
0
65
0
% N
% Pro:
0
0
0
0
0
86
0
15
0
8
0
0
8
29
8
% P
% Gln:
0
0
15
0
0
0
0
0
0
0
0
0
8
0
8
% Q
% Arg:
0
0
0
8
0
8
0
0
0
0
65
0
0
0
0
% R
% Ser:
0
0
8
8
0
8
65
58
0
79
0
8
0
0
0
% S
% Thr:
0
0
8
0
0
0
0
0
0
0
0
22
0
0
0
% T
% Val:
0
0
8
0
15
0
0
0
0
0
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _