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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EXOC5
All Species:
36.97
Human Site:
S335
Identified Species:
62.56
UniProt:
O00471
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00471
NP_006535.1
708
81853
S335
T
D
K
Q
T
F
L
S
K
L
I
K
S
I
F
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001090127
708
81848
S335
T
D
K
Q
T
F
L
S
K
L
I
K
S
I
F
Dog
Lupus familis
XP_547832
708
81807
S335
T
D
K
Q
T
F
L
S
K
L
I
K
S
I
F
Cat
Felis silvestris
Mouse
Mus musculus
Q3TPX4
708
81777
S335
T
D
K
Q
T
F
L
S
K
L
I
K
S
I
F
Rat
Rattus norvegicus
P97878
708
81718
S335
T
D
K
Q
T
F
L
S
K
L
I
K
S
I
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511952
708
81659
S335
T
D
K
Q
T
F
L
S
K
L
I
K
S
I
F
Chicken
Gallus gallus
NP_001012607
707
81709
S334
T
D
K
Q
T
F
L
S
K
L
I
K
S
I
F
Frog
Xenopus laevis
NP_001085732
708
81822
S335
T
D
K
Q
T
F
L
S
K
L
I
K
S
I
F
Zebra Danio
Brachydanio rerio
NP_001107268
708
81758
S335
S
D
K
H
T
F
L
S
K
L
I
K
N
I
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9XTM1
710
82012
Q334
T
I
D
D
D
L
L
Q
K
L
T
Q
Q
I
F
Honey Bee
Apis mellifera
XP_624953
716
82975
R340
M
Y
L
T
K
L
T
R
N
I
F
Q
K
Y
L
Nematode Worm
Caenorhab. elegans
Q18406
659
75732
D289
E
K
L
H
I
S
P
D
S
A
F
L
S
T
L
Sea Urchin
Strong. purpuratus
XP_784056
728
83314
K351
H
L
L
S
R
L
T
K
K
I
F
G
A
Y
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8RVQ5
825
89676
T416
L
A
V
A
Y
E
R
T
Q
E
L
A
K
D
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.8
99.4
N.A.
98.3
98.1
N.A.
96.7
95.4
89.8
83.3
N.A.
43.3
47.4
34.1
48.4
Protein Similarity:
100
N.A.
99.8
99.7
N.A.
99.1
99.2
N.A.
98.7
98.1
95.7
93.2
N.A.
65.3
70.5
56.5
69.6
P-Site Identity:
100
N.A.
100
100
N.A.
100
100
N.A.
100
100
100
80
N.A.
40
0
6.6
6.6
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
100
100
100
93.3
N.A.
46.6
13.3
6.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.1
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
41
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
8
0
0
0
0
0
8
0
8
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
65
8
8
8
0
0
8
0
0
0
0
0
8
0
% D
% Glu:
8
0
0
0
0
8
0
0
0
8
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
65
0
0
0
0
22
0
0
0
72
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% G
% His:
8
0
0
15
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
0
8
0
0
0
0
15
65
0
0
72
0
% I
% Lys:
0
8
65
0
8
0
0
8
79
0
0
65
15
0
0
% K
% Leu:
8
8
22
0
0
22
72
0
0
72
8
8
0
0
29
% L
% Met:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
8
0
0
0
8
0
0
% N
% Pro:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
58
0
0
0
8
8
0
0
15
8
0
0
% Q
% Arg:
0
0
0
0
8
0
8
8
0
0
0
0
0
0
0
% R
% Ser:
8
0
0
8
0
8
0
65
8
0
0
0
65
0
0
% S
% Thr:
65
0
0
8
65
0
15
8
0
0
8
0
0
8
0
% T
% Val:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
8
0
0
0
0
0
0
0
0
15
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _