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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EXOC5
All Species:
22.73
Human Site:
S153
Identified Species:
38.46
UniProt:
O00471
Number Species:
13
Phosphosite Substitution
Charge Score:
0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00471
NP_006535.1
708
81853
S153
K
S
D
V
F
T
N
S
E
K
I
K
E
A
A
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001090127
708
81848
S153
K
S
D
V
F
T
N
S
E
K
I
K
E
A
A
Dog
Lupus familis
XP_547832
708
81807
S153
K
S
D
V
F
T
N
S
E
K
I
K
E
A
A
Cat
Felis silvestris
Mouse
Mus musculus
Q3TPX4
708
81777
S153
K
S
D
V
F
T
N
S
E
K
I
K
E
A
A
Rat
Rattus norvegicus
P97878
708
81718
P153
K
S
D
V
F
T
N
P
E
K
I
K
E
A
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511952
708
81659
S153
K
S
D
V
F
T
N
S
E
K
I
K
E
A
A
Chicken
Gallus gallus
NP_001012607
707
81709
S152
K
S
D
V
F
T
N
S
E
K
I
K
E
A
A
Frog
Xenopus laevis
NP_001085732
708
81822
P153
R
S
D
V
F
N
N
P
E
K
I
K
E
A
A
Zebra Danio
Brachydanio rerio
NP_001107268
708
81758
P153
R
S
D
V
F
N
N
P
E
K
I
K
E
A
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9XTM1
710
82012
A153
V
I
V
N
D
I
F
A
D
A
A
R
L
S
E
Honey Bee
Apis mellifera
XP_624953
716
82975
D156
L
T
D
P
I
F
T
D
K
S
S
L
Y
E
A
Nematode Worm
Caenorhab. elegans
Q18406
659
75732
D110
L
N
S
M
I
F
T
D
P
D
K
L
L
E
S
Sea Urchin
Strong. purpuratus
XP_784056
728
83314
D167
P
T
A
D
I
F
N
D
P
D
K
Y
Q
E
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8RVQ5
825
89676
A217
V
A
E
A
A
S
I
A
Q
K
L
R
S
F
A
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.8
99.4
N.A.
98.3
98.1
N.A.
96.7
95.4
89.8
83.3
N.A.
43.3
47.4
34.1
48.4
Protein Similarity:
100
N.A.
99.8
99.7
N.A.
99.1
99.2
N.A.
98.7
98.1
95.7
93.2
N.A.
65.3
70.5
56.5
69.6
P-Site Identity:
100
N.A.
100
100
N.A.
100
93.3
N.A.
100
100
80
80
N.A.
0
13.3
0
13.3
P-Site Similarity:
100
N.A.
100
100
N.A.
100
93.3
N.A.
100
100
86.6
86.6
N.A.
26.6
26.6
20
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.1
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
41
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
60
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
8
8
0
0
15
0
8
8
0
0
65
86
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
72
8
8
0
0
22
8
15
0
0
0
0
0
% D
% Glu:
0
0
8
0
0
0
0
0
65
0
0
0
65
22
8
% E
% Phe:
0
0
0
0
65
22
8
0
0
0
0
0
0
8
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
0
22
8
8
0
0
0
65
0
0
0
0
% I
% Lys:
50
0
0
0
0
0
0
0
8
72
15
65
0
0
0
% K
% Leu:
15
0
0
0
0
0
0
0
0
0
8
15
15
0
0
% L
% Met:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
8
0
15
72
0
0
0
0
0
0
0
0
% N
% Pro:
8
0
0
8
0
0
0
22
15
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
8
0
0
0
8
0
0
% Q
% Arg:
15
0
0
0
0
0
0
0
0
0
0
15
0
0
0
% R
% Ser:
0
65
8
0
0
8
0
43
0
8
8
0
8
8
8
% S
% Thr:
0
15
0
0
0
50
15
0
0
0
0
0
0
0
0
% T
% Val:
15
0
8
65
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
8
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _