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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SAP18 All Species: 35.76
Human Site: S54 Identified Species: 60.51
UniProt: O00422 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O00422 NP_005861.2 153 17561 S54 S R G N V P S S E L Q I Y T W
Chimpanzee Pan troglodytes XP_509567 153 17527 S54 S R G N V P S S E L Q I Y T W
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_534536 172 19536 S73 S R G N V P S S E L Q I Y T W
Cat Felis silvestris
Mouse Mus musculus O55128 153 17577 S54 S R G N V P S S E L Q I Y T W
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516469 153 17557 S54 S R G N V P S S E L Q I Y T W
Chicken Gallus gallus NP_989643 153 17587 S54 S R G N V P S S E L Q I Y T W
Frog Xenopus laevis NP_001089273 153 17596 S54 S R G N V P S S E L Q I Y T W
Zebra Danio Brachydanio rerio NP_957014 153 17506 S54 A R G N V P S S E L Q I Y T W
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VEX9 150 17269 E52 F G N V P T N E L Q I Y T W Q
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q09250 166 18953 S54 N G G S V P P S E L Q M H T W
Sea Urchin Strong. purpuratus XP_784248 183 19677 E57 R G T V P A N E L Q I Y T W M
Poplar Tree Populus trichocarpa XP_002302551 151 17102 H52 V F T K I G D H H S N E D F A
Maize Zea mays NP_001132841 152 17110 G52 R V F T R V A G H H Q N E E F
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O64644 152 17146 H53 F T K S G G H H T S E D Y A V
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 N.A. 88.3 N.A. 98 N.A. N.A. 99.3 98.6 92.8 90.1 N.A. 58.8 N.A. 46.9 55.1
Protein Similarity: 100 99.3 N.A. 88.3 N.A. 98.6 N.A. N.A. 100 99.3 96 93.4 N.A. 76.4 N.A. 66.8 66.1
P-Site Identity: 100 100 N.A. 100 N.A. 100 N.A. N.A. 100 100 100 93.3 N.A. 0 N.A. 60 0
P-Site Similarity: 100 100 N.A. 100 N.A. 100 N.A. N.A. 100 100 100 100 N.A. 6.6 N.A. 86.6 6.6
Percent
Protein Identity: 48.3 47.7 N.A. 47 N.A. N.A.
Protein Similarity: 60.7 62 N.A. 62.7 N.A. N.A.
P-Site Identity: 0 6.6 N.A. 6.6 N.A. N.A.
P-Site Similarity: 6.6 20 N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 0 0 8 8 0 0 0 0 0 0 8 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 8 0 0 0 0 8 8 0 0 % D
% Glu: 0 0 0 0 0 0 0 15 65 0 8 8 8 8 0 % E
% Phe: 15 8 8 0 0 0 0 0 0 0 0 0 0 8 8 % F
% Gly: 0 22 65 0 8 15 0 8 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 8 15 15 8 0 0 8 0 0 % H
% Ile: 0 0 0 0 8 0 0 0 0 0 15 58 0 0 0 % I
% Lys: 0 0 8 8 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 15 65 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 8 % M
% Asn: 8 0 8 58 0 0 15 0 0 0 8 8 0 0 0 % N
% Pro: 0 0 0 0 15 65 8 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 15 72 0 0 0 8 % Q
% Arg: 15 58 0 0 8 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 50 0 0 15 0 0 58 65 0 15 0 0 0 0 0 % S
% Thr: 0 8 15 8 0 8 0 0 8 0 0 0 15 65 0 % T
% Val: 8 8 0 15 65 8 0 0 0 0 0 0 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 15 65 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 15 65 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _