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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WWP2
All Species:
9.09
Human Site:
S216
Identified Species:
18.18
UniProt:
O00308
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00308
NP_008945.2
870
98912
S216
E
Q
S
P
G
A
R
S
R
H
R
Q
P
V
K
Chimpanzee
Pan troglodytes
XP_519843
922
105197
A238
K
P
L
A
S
E
P
A
D
D
T
V
N
G
E
Rhesus Macaque
Macaca mulatta
XP_001101869
870
98735
S216
E
Q
S
P
G
A
R
S
R
H
R
Q
P
V
K
Dog
Lupus familis
XP_851140
922
104001
N264
E
Q
S
P
G
T
S
N
R
H
R
Q
P
V
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBH0
870
98742
N216
E
Q
S
P
G
A
R
N
R
H
R
Q
P
V
K
Rat
Rattus norvegicus
Q62940
887
102376
V229
E
L
E
P
G
W
V
V
L
D
Q
P
D
A
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510045
844
95264
S216
E
Q
S
P
G
T
R
S
R
H
R
Q
P
V
K
Chicken
Gallus gallus
NP_001034349
924
104070
P215
S
Q
V
P
G
R
D
P
S
S
M
A
A
A
T
Frog
Xenopus laevis
Q2TAS2
751
86306
D140
V
V
S
L
Q
S
R
D
R
I
G
S
G
G
Q
Zebra Danio
Brachydanio rerio
A9JRZ0
765
87445
L154
P
V
V
D
C
S
R
L
F
D
N
D
L
P
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9Y0H4
949
107948
G247
S
P
L
P
N
G
G
G
D
H
R
R
S
T
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P39940
809
91798
T198
S
T
L
Q
S
G
T
T
A
A
T
N
T
A
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
59.1
98.7
90.7
N.A.
95.9
34
N.A.
87.9
80
36
35.5
N.A.
52.3
N.A.
N.A.
N.A.
Protein Similarity:
100
72.3
99.3
91.6
N.A.
97.9
49.7
N.A.
90.8
84.8
51.7
51.3
N.A.
65.5
N.A.
N.A.
N.A.
P-Site Identity:
100
0
100
80
N.A.
93.3
20
N.A.
93.3
20
20
6.6
N.A.
20
N.A.
N.A.
N.A.
P-Site Similarity:
100
20
100
86.6
N.A.
100
26.6
N.A.
93.3
20
33.3
13.3
N.A.
33.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
35.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
50.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
0
25
0
9
9
9
0
9
9
25
9
% A
% Cys:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
9
0
0
9
9
17
25
0
9
9
0
9
% D
% Glu:
50
0
9
0
0
9
0
0
0
0
0
0
0
0
9
% E
% Phe:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
59
17
9
9
0
0
9
0
9
17
0
% G
% His:
0
0
0
0
0
0
0
0
0
50
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% I
% Lys:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
42
% K
% Leu:
0
9
25
9
0
0
0
9
9
0
0
0
9
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% M
% Asn:
0
0
0
0
9
0
0
17
0
0
9
9
9
0
0
% N
% Pro:
9
17
0
67
0
0
9
9
0
0
0
9
42
9
0
% P
% Gln:
0
50
0
9
9
0
0
0
0
0
9
42
0
0
17
% Q
% Arg:
0
0
0
0
0
9
50
0
50
0
50
9
0
0
0
% R
% Ser:
25
0
50
0
17
17
9
25
9
9
0
9
9
0
0
% S
% Thr:
0
9
0
0
0
17
9
9
0
0
17
0
9
9
17
% T
% Val:
9
17
17
0
0
0
9
9
0
0
0
9
0
42
0
% V
% Trp:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _