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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EIF3F
All Species:
18.18
Human Site:
S212
Identified Species:
30.77
UniProt:
O00303
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00303
NP_003745.1
357
37564
S212
S
L
Q
N
G
R
M
S
I
K
A
Y
V
S
T
Chimpanzee
Pan troglodytes
A5A6I3
361
37900
S216
S
L
Q
N
G
R
M
S
I
K
A
Y
V
S
T
Rhesus Macaque
Macaca mulatta
XP_001105893
361
37796
S216
S
L
Q
N
G
R
M
S
I
K
A
Y
V
S
T
Dog
Lupus familis
XP_534044
265
29358
Y124
G
R
M
S
I
K
A
Y
V
S
T
L
M
G
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9DCH4
361
37982
S216
G
L
Q
H
G
R
M
S
I
K
A
Y
V
S
T
Rat
Rattus norvegicus
NP_001099762
239
24531
L98
P
G
G
R
V
V
R
L
H
P
V
I
L
A
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515058
282
31367
Y141
S
R
M
S
I
K
A
Y
I
S
A
S
M
G
V
Chicken
Gallus gallus
XP_421624
332
35239
Y191
S
R
M
S
I
K
A
Y
V
S
A
P
M
G
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VN50
280
31086
V139
Y
V
C
I
Q
L
G
V
P
G
G
K
S
G
C
Honey Bee
Apis mellifera
XP_396596
285
31407
Q144
L
G
V
P
N
G
K
Q
G
S
M
F
T
P
V
Nematode Worm
Caenorhab. elegans
Q18967
294
32913
K153
V
R
A
Y
L
R
S
K
A
G
I
P
G
A
A
Sea Urchin
Strong. purpuratus
XP_001199439
281
31631
P140
V
R
Q
N
M
G
V
P
D
K
S
Q
G
T
V
Poplar Tree
Populus trichocarpa
XP_002315172
287
31517
A146
N
G
E
G
T
I
K
A
Y
V
S
V
N
L
S
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O04202
293
31844
A152
N
G
E
G
T
I
K
A
F
V
S
S
N
L
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.3
96.1
68.6
N.A.
89.4
56.2
N.A.
66.6
82
N.A.
N.A.
N.A.
38.9
39.2
22.1
45.1
Protein Similarity:
100
98.3
96.6
70.5
N.A.
91.9
57.9
N.A.
70.8
85.7
N.A.
N.A.
N.A.
54.9
52.9
40.3
59.9
P-Site Identity:
100
100
100
0
N.A.
86.6
0
N.A.
20
13.3
N.A.
N.A.
N.A.
0
0
6.6
20
P-Site Similarity:
100
100
100
26.6
N.A.
93.3
20
N.A.
40
40
N.A.
N.A.
N.A.
6.6
6.6
13.3
40
Percent
Protein Identity:
34.7
N.A.
N.A.
33
N.A.
N.A.
Protein Similarity:
53.2
N.A.
N.A.
53.7
N.A.
N.A.
P-Site Identity:
0
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
33.3
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
0
22
15
8
0
43
0
0
15
8
% A
% Cys:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
8
% C
% Asp:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% D
% Glu:
0
0
15
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
8
0
0
8
0
0
0
% F
% Gly:
15
29
8
15
29
15
8
0
8
15
8
0
15
29
0
% G
% His:
0
0
0
8
0
0
0
0
8
0
0
0
0
0
0
% H
% Ile:
0
0
0
8
22
15
0
0
36
0
8
8
0
0
0
% I
% Lys:
0
0
0
0
0
22
22
8
0
36
0
8
0
0
0
% K
% Leu:
8
29
0
0
8
8
0
8
0
0
0
8
8
15
0
% L
% Met:
0
0
22
0
8
0
29
0
0
0
8
0
22
0
0
% M
% Asn:
15
0
0
29
8
0
0
0
0
0
0
0
15
0
0
% N
% Pro:
8
0
0
8
0
0
0
8
8
8
0
15
0
8
0
% P
% Gln:
0
0
36
0
8
0
0
8
0
0
0
8
0
0
0
% Q
% Arg:
0
36
0
8
0
36
8
0
0
0
0
0
0
0
0
% R
% Ser:
36
0
0
22
0
0
8
29
0
29
22
15
8
29
22
% S
% Thr:
0
0
0
0
15
0
0
0
0
0
8
0
8
8
29
% T
% Val:
15
8
8
0
8
8
8
8
15
15
8
8
29
0
36
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
8
0
0
0
22
8
0
0
29
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _