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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LEFTY2
All Species:
24.55
Human Site:
T146
Identified Species:
54
UniProt:
O00292
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00292
NP_003231.2
366
40920
T146
R
S
A
Q
A
R
V
T
V
E
W
L
R
V
R
Chimpanzee
Pan troglodytes
XP_001138066
366
40871
T146
R
S
A
W
A
R
V
T
V
E
W
L
R
V
R
Rhesus Macaque
Macaca mulatta
XP_001092296
366
40758
T146
R
G
A
R
A
R
V
T
V
E
W
L
R
V
R
Dog
Lupus familis
XP_547508
410
45569
T189
H
S
A
R
A
R
V
T
I
E
W
L
Q
V
R
Cat
Felis silvestris
Mouse
Mus musculus
P57785
368
41157
T146
H
S
A
R
A
R
V
T
I
E
W
L
R
V
R
Rat
Rattus norvegicus
Q06826
408
46522
V184
H
R
I
N
I
Y
E
V
M
K
P
P
A
E
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512708
369
41483
E148
P
V
T
H
V
R
V
E
I
Q
W
V
H
I
R
Chicken
Gallus gallus
NP_990095
362
41161
S146
P
V
S
N
A
R
V
S
I
Y
W
V
Q
R
Q
Frog
Xenopus laevis
P25703
398
45557
D177
L
H
R
I
N
I
Y
D
I
V
K
P
A
A
A
Zebra Danio
Brachydanio rerio
NP_571036
362
41441
S150
P
I
N
H
A
R
V
S
I
Y
W
V
E
V
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001123281
399
44790
T162
L
V
S
V
N
Q
L
T
N
E
E
I
D
L
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.3
94.8
72.1
N.A.
81.2
21.3
N.A.
43.3
38.7
21.1
37.1
N.A.
N.A.
N.A.
N.A.
22
Protein Similarity:
100
96.4
96.1
79.5
N.A.
89.1
35.5
N.A.
60.4
57.3
37.1
59.2
N.A.
N.A.
N.A.
N.A.
38.1
P-Site Identity:
100
93.3
86.6
73.3
N.A.
80
0
N.A.
26.6
26.6
0
33.3
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
93.3
93.3
93.3
N.A.
93.3
13.3
N.A.
53.3
66.6
6.6
53.3
N.A.
N.A.
N.A.
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
46
0
64
0
0
0
0
0
0
0
19
10
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
10
0
0
0
0
10
0
10
% D
% Glu:
0
0
0
0
0
0
10
10
0
55
10
0
10
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
28
10
0
19
0
0
0
0
0
0
0
0
10
0
0
% H
% Ile:
0
10
10
10
10
10
0
0
55
0
0
10
0
10
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
10
10
0
0
0
0
% K
% Leu:
19
0
0
0
0
0
10
0
0
0
0
46
0
10
10
% L
% Met:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
10
% M
% Asn:
0
0
10
19
19
0
0
0
10
0
0
0
0
0
0
% N
% Pro:
28
0
0
0
0
0
0
0
0
0
10
19
0
0
0
% P
% Gln:
0
0
0
10
0
10
0
0
0
10
0
0
19
0
10
% Q
% Arg:
28
10
10
28
0
73
0
0
0
0
0
0
37
10
55
% R
% Ser:
0
37
19
0
0
0
0
19
0
0
0
0
0
0
0
% S
% Thr:
0
0
10
0
0
0
0
55
0
0
0
0
0
0
0
% T
% Val:
0
28
0
10
10
0
73
10
28
10
0
28
0
55
0
% V
% Trp:
0
0
0
10
0
0
0
0
0
0
73
0
0
0
0
% W
% Tyr:
0
0
0
0
0
10
10
0
0
19
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _