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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CBX4
All Species:
1.21
Human Site:
S333
Identified Species:
3.33
UniProt:
O00257
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00257
NP_003646.2
560
61368
S333
K
R
R
E
E
E
V
S
G
V
S
D
P
Q
P
Chimpanzee
Pan troglodytes
XP_523736
378
42282
E173
R
E
R
E
R
E
R
E
R
E
R
E
R
G
T
Rhesus Macaque
Macaca mulatta
XP_001109437
837
88730
A531
S
H
P
P
D
K
W
A
Q
G
A
G
A
K
G
Dog
Lupus familis
XP_850702
632
67994
G413
R
R
E
E
E
A
P
G
P
G
D
P
Q
P
Q
Cat
Felis silvestris
Mouse
Mus musculus
O55187
551
60504
L334
K
R
R
E
E
E
A
L
V
S
G
D
A
Q
P
Rat
Rattus norvegicus
P60889
158
17948
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_989973
523
58166
V312
K
P
G
E
E
R
A
V
G
S
N
G
L
S
A
Frog
Xenopus laevis
NP_001080949
521
58786
T310
G
T
L
N
G
D
K
T
C
T
A
Q
E
E
K
Zebra Danio
Brachydanio rerio
NP_991312
477
54249
K272
V
M
S
K
Y
M
D
K
G
V
H
S
S
K
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
25.1
58.2
78.4
N.A.
89.6
20.7
N.A.
N.A.
62.1
49.4
42.6
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
36.9
59.5
80.6
N.A.
91.9
24.8
N.A.
N.A.
68.7
60.8
55.5
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
20
0
20
N.A.
60
0
N.A.
N.A.
26.6
0
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
33.3
33.3
26.6
N.A.
60
0
N.A.
N.A.
33.3
26.6
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
12
23
12
0
0
23
0
23
0
12
% A
% Cys:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
12
12
12
0
0
0
12
23
0
0
0
% D
% Glu:
0
12
12
56
45
34
0
12
0
12
0
12
12
12
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
12
0
12
0
12
0
0
12
34
23
12
23
0
12
12
% G
% His:
0
12
0
0
0
0
0
0
0
0
12
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
34
0
0
12
0
12
12
12
0
0
0
0
0
23
12
% K
% Leu:
0
0
12
0
0
0
0
12
0
0
0
0
12
0
0
% L
% Met:
0
12
0
0
0
12
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
12
0
0
0
0
0
0
12
0
0
0
0
% N
% Pro:
0
12
12
12
0
0
12
0
12
0
0
12
12
12
23
% P
% Gln:
0
0
0
0
0
0
0
0
12
0
0
12
12
23
12
% Q
% Arg:
23
34
34
0
12
12
12
0
12
0
12
0
12
0
0
% R
% Ser:
12
0
12
0
0
0
0
12
0
23
12
12
12
12
0
% S
% Thr:
0
12
0
0
0
0
0
12
0
12
0
0
0
0
12
% T
% Val:
12
0
0
0
0
0
12
12
12
23
0
0
0
0
12
% V
% Trp:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _