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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GRM8
All Species:
27.27
Human Site:
S373
Identified Species:
60
UniProt:
O00222
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00222
NP_000836.2
908
101741
S373
N
F
G
C
K
L
G
S
H
G
K
R
N
S
H
Chimpanzee
Pan troglodytes
A3QNZ8
839
95029
H318
H
N
L
T
E
L
R
H
L
G
T
F
L
G
I
Rhesus Macaque
Macaca mulatta
XP_001088843
908
101770
S373
N
F
G
C
K
L
G
S
H
G
K
R
N
S
H
Dog
Lupus familis
XP_859005
908
101622
S373
N
F
G
C
K
L
G
S
H
G
K
R
N
S
H
Cat
Felis silvestris
Mouse
Mus musculus
P47743
908
101809
S373
N
F
G
C
K
L
G
S
H
G
K
R
N
S
H
Rat
Rattus norvegicus
P70579
908
101848
S373
N
F
G
C
K
L
G
S
H
G
K
R
N
S
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508620
908
101703
S373
N
F
G
C
K
L
G
S
H
G
K
R
N
S
H
Chicken
Gallus gallus
XP_425426
924
103611
S373
N
F
G
C
K
L
G
S
H
G
K
R
N
S
N
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q5U9X3
867
97118
Q342
G
N
F
T
S
F
H
Q
Y
L
K
N
L
Q
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91685
976
108467
D389
S
N
S
A
N
S
T
D
N
K
I
G
V
K
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09630
999
113258
C427
L
W
Q
V
K
Y
K
C
E
F
D
T
P
P
G
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
23.4
99.5
98.6
N.A.
98.4
98.5
N.A.
96.1
91.4
N.A.
26.1
N.A.
44.7
N.A.
36.4
N.A.
Protein Similarity:
100
41.8
99.7
99.4
N.A.
99.3
99.2
N.A.
98.7
95.1
N.A.
44.2
N.A.
59.7
N.A.
54.6
N.A.
P-Site Identity:
100
13.3
100
100
N.A.
100
100
N.A.
100
93.3
N.A.
6.6
N.A.
0
N.A.
6.6
N.A.
P-Site Similarity:
100
26.6
100
100
N.A.
100
100
N.A.
100
100
N.A.
13.3
N.A.
13.3
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
10
% A
% Cys:
0
0
0
64
0
0
0
10
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
10
0
0
10
0
0
0
0
% D
% Glu:
0
0
0
0
10
0
0
0
10
0
0
0
0
0
0
% E
% Phe:
0
64
10
0
0
10
0
0
0
10
0
10
0
0
10
% F
% Gly:
10
0
64
0
0
0
64
0
0
73
0
10
0
10
10
% G
% His:
10
0
0
0
0
0
10
10
64
0
0
0
0
0
55
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
10
% I
% Lys:
0
0
0
0
73
0
10
0
0
10
73
0
0
10
0
% K
% Leu:
10
0
10
0
0
73
0
0
10
10
0
0
19
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
64
28
0
0
10
0
0
0
10
0
0
10
64
0
10
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
10
10
0
% P
% Gln:
0
0
10
0
0
0
0
10
0
0
0
0
0
10
0
% Q
% Arg:
0
0
0
0
0
0
10
0
0
0
0
64
0
0
0
% R
% Ser:
10
0
10
0
10
10
0
64
0
0
0
0
0
64
0
% S
% Thr:
0
0
0
19
0
0
10
0
0
0
10
10
0
0
0
% T
% Val:
0
0
0
10
0
0
0
0
0
0
0
0
10
0
0
% V
% Trp:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
10
0
0
10
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _