KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GRM8
All Species:
26.67
Human Site:
S250
Identified Species:
58.67
UniProt:
O00222
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00222
NP_000836.2
908
101741
S250
G
G
V
C
I
A
Q
S
Q
K
I
P
R
E
P
Chimpanzee
Pan troglodytes
A3QNZ8
839
95029
G224
R
D
N
G
Q
L
L
G
E
R
L
A
R
R
D
Rhesus Macaque
Macaca mulatta
XP_001088843
908
101770
S250
G
G
V
C
I
A
Q
S
Q
K
I
P
R
E
P
Dog
Lupus familis
XP_859005
908
101622
S250
G
G
V
C
I
A
Q
S
Q
K
I
P
R
E
P
Cat
Felis silvestris
Mouse
Mus musculus
P47743
908
101809
S250
G
G
V
C
I
A
Q
S
Q
K
I
P
R
E
P
Rat
Rattus norvegicus
P70579
908
101848
S250
G
G
V
C
I
A
Q
S
Q
K
I
P
R
E
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508620
908
101703
S250
G
G
V
C
I
A
Q
S
L
K
I
P
R
E
P
Chicken
Gallus gallus
XP_425426
924
103611
S250
G
G
V
C
I
A
Q
S
L
K
I
P
R
E
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q5U9X3
867
97118
A244
G
I
C
I
A
F
K
A
I
L
P
D
S
L
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91685
976
108467
E252
N
V
C
I
A
V
A
E
K
V
P
S
A
A
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09630
999
113258
E296
G
I
C
I
A
L
E
E
R
I
Q
N
K
K
E
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
23.4
99.5
98.6
N.A.
98.4
98.5
N.A.
96.1
91.4
N.A.
26.1
N.A.
44.7
N.A.
36.4
N.A.
Protein Similarity:
100
41.8
99.7
99.4
N.A.
99.3
99.2
N.A.
98.7
95.1
N.A.
44.2
N.A.
59.7
N.A.
54.6
N.A.
P-Site Identity:
100
6.6
100
100
N.A.
100
100
N.A.
93.3
93.3
N.A.
6.6
N.A.
0
N.A.
6.6
N.A.
P-Site Similarity:
100
26.6
100
100
N.A.
100
100
N.A.
93.3
93.3
N.A.
20
N.A.
6.6
N.A.
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
28
64
10
10
0
0
0
10
10
10
10
% A
% Cys:
0
0
28
64
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
0
0
0
0
0
0
0
10
0
0
19
% D
% Glu:
0
0
0
0
0
0
10
19
10
0
0
0
0
64
10
% E
% Phe:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% F
% Gly:
82
64
0
10
0
0
0
10
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
19
0
28
64
0
0
0
10
10
64
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
10
0
10
64
0
0
10
10
0
% K
% Leu:
0
0
0
0
0
19
10
0
19
10
10
0
0
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
10
0
0
0
0
0
0
0
0
10
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
19
64
0
0
64
% P
% Gln:
0
0
0
0
10
0
64
0
46
0
10
0
0
0
0
% Q
% Arg:
10
0
0
0
0
0
0
0
10
10
0
0
73
10
0
% R
% Ser:
0
0
0
0
0
0
0
64
0
0
0
10
10
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
10
64
0
0
10
0
0
0
10
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _