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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LGALS8
All Species:
21.21
Human Site:
S154
Identified Species:
46.67
UniProt:
O00214
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00214
NP_006490.3
317
35808
S154
H
S
I
G
F
S
F
S
S
D
L
Q
S
T
Q
Chimpanzee
Pan troglodytes
XP_001157677
317
35660
S154
H
S
I
G
F
S
F
S
S
V
L
Q
S
T
Q
Rhesus Macaque
Macaca mulatta
XP_001098674
317
35855
S154
H
S
I
G
F
R
F
S
S
D
L
Q
S
T
Q
Dog
Lupus familis
XP_536335
357
40379
S153
H
S
I
G
Y
S
F
S
S
D
F
R
S
T
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9JL15
316
36143
S153
H
S
I
G
F
R
F
S
S
D
L
Q
S
M
E
Rat
Rattus norvegicus
Q62665
316
36020
S153
H
S
I
G
F
R
F
S
S
D
L
Q
S
M
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZHQ2
171
19026
K12
V
A
E
R
D
A
P
K
I
E
D
G
H
L
N
Frog
Xenopus laevis
Q68FJ4
171
19166
Q12
L
V
E
S
E
A
L
Q
M
G
V
R
R
L
S
Zebra Danio
Brachydanio rerio
Q1ECW6
164
18441
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09581
297
33622
H138
D
G
D
V
V
L
N
H
V
Q
W
G
G
K
Y
Sea Urchin
Strong. purpuratus
XP_781871
278
31504
S121
D
G
K
V
Q
I
H
S
I
R
F
Q
G
Q
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.1
96.2
77
N.A.
79.5
80.1
N.A.
N.A.
23.6
21.7
20.8
N.A.
N.A.
N.A.
25.8
39.1
Protein Similarity:
100
99.3
97.4
82
N.A.
89.9
89.5
N.A.
N.A.
37.2
35
33.7
N.A.
N.A.
N.A.
42.5
55.5
P-Site Identity:
100
93.3
93.3
80
N.A.
80
80
N.A.
N.A.
0
0
0
N.A.
N.A.
N.A.
0
13.3
P-Site Similarity:
100
93.3
93.3
93.3
N.A.
86.6
86.6
N.A.
N.A.
20
20
0
N.A.
N.A.
N.A.
0
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
19
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
19
0
10
0
10
0
0
0
0
46
10
0
0
0
0
% D
% Glu:
0
0
19
0
10
0
0
0
0
10
0
0
0
0
19
% E
% Phe:
0
0
0
0
46
0
55
0
0
0
19
0
0
0
0
% F
% Gly:
0
19
0
55
0
0
0
0
0
10
0
19
19
0
0
% G
% His:
55
0
0
0
0
0
10
10
0
0
0
0
10
0
0
% H
% Ile:
0
0
55
0
0
10
0
0
19
0
0
0
0
0
0
% I
% Lys:
0
0
10
0
0
0
0
10
0
0
0
0
0
10
0
% K
% Leu:
10
0
0
0
0
10
10
0
0
0
46
0
0
19
0
% L
% Met:
0
0
0
0
0
0
0
0
10
0
0
0
0
19
0
% M
% Asn:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
10
% N
% Pro:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
10
0
0
10
0
10
0
55
0
10
37
% Q
% Arg:
0
0
0
10
0
28
0
0
0
10
0
19
10
0
0
% R
% Ser:
0
55
0
10
0
28
0
64
55
0
0
0
55
0
19
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
37
0
% T
% Val:
10
10
0
19
10
0
0
0
10
10
10
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% W
% Tyr:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _