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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ARVCF All Species: 26.06
Human Site: S345 Identified Species: 57.33
UniProt: O00192 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O00192 NP_001661.1 962 104642 S345 R L V R R S P S V D S A R K E
Chimpanzee Pan troglodytes XP_514985 935 101610 S345 R L V R R S P S V D S A R K E
Rhesus Macaque Macaca mulatta XP_001105468 962 104658 S345 R L V R R S P S V D S A R K E
Dog Lupus familis XP_543543 959 104232 S343 R V V R R S P S V D S A R K E
Cat Felis silvestris
Mouse Mus musculus P98203 962 105047 S347 R V V R R S P S V D S T R K E
Rat Rattus norvegicus NP_001124485 973 105468 S346 R V V R R S P S V D S T R K E
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_989796 983 109688 S374 R L G K R S P S I D S I R K D
Frog Xenopus laevis Q8AXM9 859 94542 A310 A V R L N A A A Y L Q H L S Y
Zebra Danio Brachydanio rerio NP_001122006 986 110482 P377 R M G G R R S P S I D S I R K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q9U308 1254 138340 N626 V H I E P S T N R F S S D T M
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9C9A6 628 68956 A119 V T W K L E K A L G D L T Y D
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.1 97.7 94.4 N.A. 91.6 88.3 N.A. N.A. 68.4 40.2 65.5 N.A. N.A. N.A. 24.7 N.A.
Protein Similarity: 100 96.4 98.1 96 N.A. 94.4 91.1 N.A. N.A. 79.7 56.9 77.6 N.A. N.A. N.A. 38.7 N.A.
P-Site Identity: 100 100 100 93.3 N.A. 86.6 86.6 N.A. N.A. 66.6 0 13.3 N.A. N.A. N.A. 13.3 N.A.
P-Site Similarity: 100 100 100 100 N.A. 93.3 93.3 N.A. N.A. 86.6 20 40 N.A. N.A. N.A. 33.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 20 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 35 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 0 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 0 0 10 10 19 0 0 0 37 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 64 19 0 10 0 19 % D
% Glu: 0 0 0 10 0 10 0 0 0 0 0 0 0 0 55 % E
% Phe: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % F
% Gly: 0 0 19 10 0 0 0 0 0 10 0 0 0 0 0 % G
% His: 0 10 0 0 0 0 0 0 0 0 0 10 0 0 0 % H
% Ile: 0 0 10 0 0 0 0 0 10 10 0 10 10 0 0 % I
% Lys: 0 0 0 19 0 0 10 0 0 0 0 0 0 64 10 % K
% Leu: 0 37 0 10 10 0 0 0 10 10 0 10 10 0 0 % L
% Met: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 10 % M
% Asn: 0 0 0 0 10 0 0 10 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 10 0 64 10 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % Q
% Arg: 73 0 10 55 73 10 0 0 10 0 0 0 64 10 0 % R
% Ser: 0 0 0 0 0 73 10 64 10 0 73 19 0 10 0 % S
% Thr: 0 10 0 0 0 0 10 0 0 0 0 19 10 10 0 % T
% Val: 19 37 55 0 0 0 0 0 55 0 0 0 0 0 0 % V
% Trp: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 10 0 0 0 0 10 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _