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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MYO1F All Species: 9.7
Human Site: S973 Identified Species: 17.78
UniProt: O00160 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O00160 NP_036467.2 1098 124844 S973 P L P L E I M S G G G T H R P
Chimpanzee Pan troglodytes XP_512345 1254 142059 S1129 P L P L E I M S G G G T H R P
Rhesus Macaque Macaca mulatta XP_001100995 715 80188 G600 S S H R P P R G P P S T S L G
Dog Lupus familis XP_542129 1121 127316 S996 P L P L E I T S G G G S Q Q P
Cat Felis silvestris
Mouse Mus musculus P70248 1099 125929 W975 Y T L E I Y I W P Q E F P E A
Rat Rattus norvegicus Q63356 1107 126808 H972 L T R N Q F V H P P R A S G N
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZLA6 1028 118889 A911 Q L L L T Q N A V I I V E D S
Frog Xenopus laevis NP_001086041 1096 125695 S971 G T A R N P S S A Q S S R Q P
Zebra Danio Brachydanio rerio XP_001921060 1136 130657 P1010 K E V T Y S M P V R H N P P P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_492393 1100 124867 G977 R A P V P A H G M N N N Y N Q
Sea Urchin Strong. purpuratus NP_001118234 1118 127023 A969 P A P G K P T A P Y A L V Q K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q04439 1219 136881 N1020 P P P P G M Q N K A A T R R S
Red Bread Mold Neurospora crassa Q7SDM3 1235 136290 G1010 R T A Q P R P G G G P S I A A
Conservation
Percent
Protein Identity: 100 78.3 64.4 89.3 N.A. 90.1 71.2 N.A. N.A. 35.7 79.3 74.2 N.A. N.A. N.A. 56 62.8
Protein Similarity: 100 81.1 64.7 92.2 N.A. 94.4 83.9 N.A. N.A. 53.9 88.8 83.2 N.A. N.A. N.A. 71.2 77.2
P-Site Identity: 100 100 6.6 73.3 N.A. 0 0 N.A. N.A. 13.3 13.3 13.3 N.A. N.A. N.A. 6.6 13.3
P-Site Similarity: 100 100 6.6 86.6 N.A. 6.6 13.3 N.A. N.A. 20 26.6 13.3 N.A. N.A. N.A. 20 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 38.3 37.4
Protein Similarity: N.A. N.A. N.A. N.A. 56.3 54.4
P-Site Identity: N.A. N.A. N.A. N.A. 26.6 13.3
P-Site Similarity: N.A. N.A. N.A. N.A. 40 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 16 16 0 0 8 0 16 8 8 16 8 0 8 16 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % D
% Glu: 0 8 0 8 24 0 0 0 0 0 8 0 8 8 0 % E
% Phe: 0 0 0 0 0 8 0 0 0 0 0 8 0 0 0 % F
% Gly: 8 0 0 8 8 0 0 24 31 31 24 0 0 8 8 % G
% His: 0 0 8 0 0 0 8 8 0 0 8 0 16 0 0 % H
% Ile: 0 0 0 0 8 24 8 0 0 8 8 0 8 0 0 % I
% Lys: 8 0 0 0 8 0 0 0 8 0 0 0 0 0 8 % K
% Leu: 8 31 16 31 0 0 0 0 0 0 0 8 0 8 0 % L
% Met: 0 0 0 0 0 8 24 0 8 0 0 0 0 0 0 % M
% Asn: 0 0 0 8 8 0 8 8 0 8 8 16 0 8 8 % N
% Pro: 39 8 47 8 24 24 8 8 31 16 8 0 16 8 39 % P
% Gln: 8 0 0 8 8 8 8 0 0 16 0 0 8 24 8 % Q
% Arg: 16 0 8 16 0 8 8 0 0 8 8 0 16 24 0 % R
% Ser: 8 8 0 0 0 8 8 31 0 0 16 24 16 0 16 % S
% Thr: 0 31 0 8 8 0 16 0 0 0 0 31 0 0 0 % T
% Val: 0 0 8 8 0 0 8 0 16 0 0 8 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % W
% Tyr: 8 0 0 0 8 8 0 0 0 8 0 0 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _