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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDX39
All Species:
28.18
Human Site:
S183
Identified Species:
41.33
UniProt:
O00148
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00148
NP_005795.2
427
49130
S183
L
A
L
V
R
N
R
S
F
S
L
K
N
V
K
Chimpanzee
Pan troglodytes
XP_001171771
416
46980
S183
L
A
L
V
R
N
R
S
F
S
L
K
N
V
K
Rhesus Macaque
Macaca mulatta
XP_001112060
544
61883
K307
S
F
S
L
K
N
V
K
H
F
V
L
D
E
C
Dog
Lupus familis
XP_533895
427
49073
S183
L
A
L
V
R
N
R
S
L
N
L
K
N
V
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8VDW0
427
49049
S183
L
A
L
V
R
S
R
S
L
N
L
R
N
V
K
Rat
Rattus norvegicus
Q5U216
427
49091
S183
L
A
L
V
R
S
R
S
L
N
L
R
N
V
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515366
430
49724
K183
L
A
L
V
R
N
K
K
L
S
L
K
Y
V
K
Chicken
Gallus gallus
Q5ZHZ0
428
48985
S184
L
A
L
A
R
N
K
S
L
N
L
K
H
I
K
Frog
Xenopus laevis
NP_001079623
427
49158
I183
L
A
L
V
R
S
K
I
L
N
L
K
N
V
K
Zebra Danio
Brachydanio rerio
NP_998142
427
48929
T183
L
A
L
V
R
N
K
T
L
N
L
K
N
V
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q27268
424
48633
K181
L
A
L
I
R
N
K
K
L
N
L
K
L
L
K
Honey Bee
Apis mellifera
XP_624894
424
48776
K181
L
A
L
V
R
N
K
K
L
N
L
K
H
L
K
Nematode Worm
Caenorhab. elegans
Q18212
425
48474
K180
L
A
L
A
R
S
G
K
L
K
L
D
K
V
K
Sea Urchin
Strong. purpuratus
XP_779919
429
49042
I186
L
A
L
G
R
Q
K
I
L
N
L
K
H
V
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LFN6
427
48319
D185
L
A
L
A
R
E
K
D
L
S
L
K
N
V
R
Baker's Yeast
Sacchar. cerevisiae
Q07478
446
50290
Y203
K
A
L
V
R
E
K
Y
I
D
L
S
H
V
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.9
76.2
97.8
N.A.
97.1
96.7
N.A.
76.5
89.9
90.4
91.8
N.A.
82.1
82.4
75.8
82.2
Protein Similarity:
100
89.9
76.4
99.5
N.A.
99.7
99.5
N.A.
89.5
96.7
96.4
97.1
N.A.
91.8
91.5
87.5
90.9
P-Site Identity:
100
100
6.6
86.6
N.A.
73.3
73.3
N.A.
73.3
60
66.6
73.3
N.A.
53.3
60
46.6
53.3
P-Site Similarity:
100
100
33.3
93.3
N.A.
93.3
93.3
N.A.
80
86.6
86.6
93.3
N.A.
80
86.6
53.3
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
70.4
62.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
84.3
78
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
60
46.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
73.3
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
94
0
19
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% C
% Asp:
0
0
0
0
0
0
0
7
0
7
0
7
7
0
0
% D
% Glu:
0
0
0
0
0
13
0
0
0
0
0
0
0
7
0
% E
% Phe:
0
7
0
0
0
0
0
0
13
7
0
0
0
0
0
% F
% Gly:
0
0
0
7
0
0
7
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
7
0
0
0
25
0
0
% H
% Ile:
0
0
0
7
0
0
0
13
7
0
0
0
0
7
0
% I
% Lys:
7
0
0
0
7
0
57
32
0
7
0
69
7
0
88
% K
% Leu:
88
0
94
7
0
0
0
0
75
0
94
7
7
13
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
57
0
0
0
57
0
0
50
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
94
0
32
0
0
0
0
13
0
0
7
% R
% Ser:
7
0
7
0
0
25
0
38
0
25
0
7
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% T
% Val:
0
0
0
63
0
0
7
0
0
0
7
0
0
75
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
7
0
0
0
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _