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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDX39
All Species:
63.94
Human Site:
S136
Identified Species:
93.78
UniProt:
O00148
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00148
NP_005795.2
427
49130
S136
S
K
E
Y
E
R
F
S
K
Y
M
P
S
V
K
Chimpanzee
Pan troglodytes
XP_001171771
416
46980
S136
G
K
E
Y
E
R
F
S
K
Y
M
P
S
V
K
Rhesus Macaque
Macaca mulatta
XP_001112060
544
61883
S264
S
K
E
Y
E
R
F
S
K
Y
M
P
S
V
K
Dog
Lupus familis
XP_533895
427
49073
S136
S
K
E
Y
E
R
F
S
K
Y
M
P
S
V
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8VDW0
427
49049
S136
S
K
E
Y
E
R
F
S
K
Y
M
P
S
V
K
Rat
Rattus norvegicus
Q5U216
427
49091
S136
S
K
E
Y
E
R
F
S
K
Y
M
P
S
V
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515366
430
49724
S136
S
K
E
F
Q
R
F
S
K
Y
M
P
K
V
K
Chicken
Gallus gallus
Q5ZHZ0
428
48985
S137
S
K
E
Y
E
R
F
S
K
Y
M
P
S
V
K
Frog
Xenopus laevis
NP_001079623
427
49158
S136
S
K
E
Y
E
R
F
S
K
Y
M
P
T
V
K
Zebra Danio
Brachydanio rerio
NP_998142
427
48929
S136
S
K
E
Y
E
R
F
S
K
Y
M
P
T
V
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q27268
424
48633
S134
S
K
E
Y
E
R
F
S
K
Y
M
P
T
V
K
Honey Bee
Apis mellifera
XP_624894
424
48776
S134
S
K
E
Y
E
R
F
S
K
Y
M
P
H
V
K
Nematode Worm
Caenorhab. elegans
Q18212
425
48474
S133
S
K
E
Y
E
R
F
S
K
Y
L
P
G
V
K
Sea Urchin
Strong. purpuratus
XP_779919
429
49042
S139
A
K
E
Y
E
R
F
S
K
Y
M
P
T
V
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LFN6
427
48319
S138
C
N
E
F
V
R
F
S
T
Y
L
P
D
T
K
Baker's Yeast
Sacchar. cerevisiae
Q07478
446
50290
S154
R
N
E
Y
L
R
F
S
K
Y
M
P
D
V
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.9
76.2
97.8
N.A.
97.1
96.7
N.A.
76.5
89.9
90.4
91.8
N.A.
82.1
82.4
75.8
82.2
Protein Similarity:
100
89.9
76.4
99.5
N.A.
99.7
99.5
N.A.
89.5
96.7
96.4
97.1
N.A.
91.8
91.5
87.5
90.9
P-Site Identity:
100
93.3
100
100
N.A.
100
100
N.A.
80
100
93.3
93.3
N.A.
93.3
93.3
86.6
86.6
P-Site Similarity:
100
93.3
100
100
N.A.
100
100
N.A.
93.3
100
100
100
N.A.
100
93.3
93.3
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
70.4
62.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
84.3
78
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
46.6
73.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
60
73.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
13
0
0
% D
% Glu:
0
0
100
0
82
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
13
0
0
100
0
0
0
0
0
0
0
0
% F
% Gly:
7
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
88
0
0
0
0
0
0
94
0
0
0
7
0
100
% K
% Leu:
0
0
0
0
7
0
0
0
0
0
13
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
88
0
0
0
0
% M
% Asn:
0
13
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
100
0
0
0
% P
% Gln:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
7
0
0
0
0
100
0
0
0
0
0
0
0
0
0
% R
% Ser:
75
0
0
0
0
0
0
100
0
0
0
0
44
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
7
0
0
0
25
7
0
% T
% Val:
0
0
0
0
7
0
0
0
0
0
0
0
0
94
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
88
0
0
0
0
0
100
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _