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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FZD9 All Species: 26.06
Human Site: Y82 Identified Species: 52.12
UniProt: O00144 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O00144 NP_003499.1 591 64466 Y82 E F A P L V Q Y G C H S H L R
Chimpanzee Pan troglodytes XP_527779 484 53212 G18 A T V C W T D G L A W T L D P
Rhesus Macaque Macaca mulatta XP_001109720 567 63652 Y63 E F A P L V E Y G C H G H L R
Dog Lupus familis XP_546927 594 64924 Y82 E F A P L V Q Y G C H S H L R
Cat Felis silvestris
Mouse Mus musculus Q9R216 592 64976 Y83 E F S P L V Q Y G C H S H L R
Rat Rattus norvegicus Q9QZH0 538 60336 F38 L Q R P A L G F G D E E E R R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520614 537 59681 F42 C H G H L R F F L C S L Y A P
Chicken Gallus gallus Q9PWH2 585 65927 Y81 E F A P L V E Y G C H G H L K
Frog Xenopus laevis Q9DEB5 586 65560 Y83 E F A P L V E Y G C H S H L K
Zebra Danio Brachydanio rerio NP_571586 577 64904 Y80 E F A P L V E Y G C D V H L R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P18537 581 64829 I96 Q F A P L V K I G C S D D L Q
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_790565 610 68431 V77 E F H P L V V V G C A E H L R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 71.5 61.7 96.6 N.A. 95.6 47.8 N.A. 60 63.7 62.9 71.4 N.A. 36.7 N.A. N.A. 47
Protein Similarity: 100 74.2 75.6 97.3 N.A. 96.7 64.3 N.A. 71.5 78.3 77.5 81.3 N.A. 53.6 N.A. N.A. 64.2
P-Site Identity: 100 0 86.6 100 N.A. 93.3 20 N.A. 13.3 80 86.6 80 N.A. 53.3 N.A. N.A. 66.6
P-Site Similarity: 100 6.6 93.3 100 N.A. 100 33.3 N.A. 26.6 93.3 100 86.6 N.A. 73.3 N.A. N.A. 66.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 59 0 9 0 0 0 0 9 9 0 0 9 0 % A
% Cys: 9 0 0 9 0 0 0 0 0 84 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 9 0 0 9 9 9 9 9 0 % D
% Glu: 67 0 0 0 0 0 34 0 0 0 9 17 9 0 0 % E
% Phe: 0 75 0 0 0 0 9 17 0 0 0 0 0 0 0 % F
% Gly: 0 0 9 0 0 0 9 9 84 0 0 17 0 0 0 % G
% His: 0 9 9 9 0 0 0 0 0 0 50 0 67 0 0 % H
% Ile: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 17 % K
% Leu: 9 0 0 0 84 9 0 0 17 0 0 9 9 75 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 84 0 0 0 0 0 0 0 0 0 0 17 % P
% Gln: 9 9 0 0 0 0 25 0 0 0 0 0 0 0 9 % Q
% Arg: 0 0 9 0 0 9 0 0 0 0 0 0 0 9 59 % R
% Ser: 0 0 9 0 0 0 0 0 0 0 17 34 0 0 0 % S
% Thr: 0 9 0 0 0 9 0 0 0 0 0 9 0 0 0 % T
% Val: 0 0 9 0 0 75 9 9 0 0 0 9 0 0 0 % V
% Trp: 0 0 0 0 9 0 0 0 0 0 9 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 59 0 0 0 0 9 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _