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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FZD9
All Species:
14.85
Human Site:
T581
Identified Species:
29.7
UniProt:
O00144
Number Species:
11
Phosphosite Substitution
Charge Score:
0.36
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00144
NP_003499.1
591
64466
T581
V
V
L
H
M
T
K
T
D
P
S
L
E
N
P
Chimpanzee
Pan troglodytes
XP_527779
484
53212
T474
V
V
L
H
M
T
K
T
D
P
S
L
E
N
P
Rhesus Macaque
Macaca mulatta
XP_001109720
567
63652
E558
K
T
H
H
G
K
Y
E
I
P
A
Q
P
P
T
Dog
Lupus familis
XP_546927
594
64924
T584
V
V
L
H
M
T
K
T
D
P
S
L
E
N
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9R216
592
64976
T582
V
V
L
H
M
T
K
T
D
P
S
L
E
N
P
Rat
Rattus norvegicus
Q9QZH0
538
60336
N525
V
K
R
E
K
R
G
N
G
W
V
K
P
G
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520614
537
59681
E528
K
A
R
H
G
K
Y
E
A
A
L
Q
P
P
T
Chicken
Gallus gallus
Q9PWH2
585
65927
E576
K
T
H
L
A
K
Y
E
S
T
L
Q
P
P
T
Frog
Xenopus laevis
Q9DEB5
586
65560
E577
K
V
H
H
G
K
Y
E
S
A
L
Q
S
P
T
Zebra Danio
Brachydanio rerio
NP_571586
577
64904
D568
I
L
H
M
S
K
T
D
P
Y
S
D
C
P
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P18537
581
64829
K571
F
V
E
R
L
Q
G
K
E
P
R
T
R
A
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790565
610
68431
T596
I
N
G
N
N
R
S
T
G
I
V
Y
S
S
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
71.5
61.7
96.6
N.A.
95.6
47.8
N.A.
60
63.7
62.9
71.4
N.A.
36.7
N.A.
N.A.
47
Protein Similarity:
100
74.2
75.6
97.3
N.A.
96.7
64.3
N.A.
71.5
78.3
77.5
81.3
N.A.
53.6
N.A.
N.A.
64.2
P-Site Identity:
100
100
13.3
100
N.A.
100
6.6
N.A.
6.6
0
13.3
6.6
N.A.
13.3
N.A.
N.A.
6.6
P-Site Similarity:
100
100
20
100
N.A.
100
6.6
N.A.
6.6
0
13.3
20
N.A.
26.6
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
9
0
0
0
9
17
9
0
0
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% C
% Asp:
0
0
0
0
0
0
0
9
34
0
0
9
0
0
0
% D
% Glu:
0
0
9
9
0
0
0
34
9
0
0
0
34
0
0
% E
% Phe:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
9
0
25
0
17
0
17
0
0
0
0
9
0
% G
% His:
0
0
34
59
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
17
0
0
0
0
0
0
0
9
9
0
0
0
0
0
% I
% Lys:
34
9
0
0
9
42
34
9
0
0
0
9
0
0
9
% K
% Leu:
0
9
34
9
9
0
0
0
0
0
25
34
0
0
0
% L
% Met:
0
0
0
9
34
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
9
0
9
9
0
0
9
0
0
0
0
0
34
0
% N
% Pro:
0
0
0
0
0
0
0
0
9
50
0
0
34
42
34
% P
% Gln:
0
0
0
0
0
9
0
0
0
0
0
34
0
0
9
% Q
% Arg:
0
0
17
9
0
17
0
0
0
0
9
0
9
0
0
% R
% Ser:
0
0
0
0
9
0
9
0
17
0
42
0
17
9
0
% S
% Thr:
0
17
0
0
0
34
9
42
0
9
0
9
0
0
42
% T
% Val:
42
50
0
0
0
0
0
0
0
0
17
0
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
34
0
0
9
0
9
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _