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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FZD9
All Species:
6.67
Human Site:
S560
Identified Species:
13.33
UniProt:
O00144
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00144
NP_003499.1
591
64466
S560
K
A
C
R
A
P
G
S
Y
G
R
G
T
H
C
Chimpanzee
Pan troglodytes
XP_527779
484
53212
S453
K
A
C
R
A
P
G
S
Y
G
R
G
T
H
C
Rhesus Macaque
Macaca mulatta
XP_001109720
567
63652
I537
R
R
K
P
A
S
V
I
T
S
G
G
I
Y
K
Dog
Lupus familis
XP_546927
594
64924
G563
K
A
C
R
A
S
G
G
Y
G
R
G
T
H
C
Cat
Felis silvestris
Mouse
Mus musculus
Q9R216
592
64976
G561
K
A
C
R
T
P
G
G
Y
G
R
G
T
H
C
Rat
Rattus norvegicus
Q9QZH0
538
60336
T504
W
S
A
K
T
L
H
T
W
Q
K
C
S
N
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520614
537
59681
I507
R
R
K
P
A
G
V
I
A
G
A
G
I
Y
K
Chicken
Gallus gallus
Q9PWH2
585
65927
I555
R
R
K
P
A
S
V
I
T
S
S
G
I
Y
K
Frog
Xenopus laevis
Q9DEB5
586
65560
I556
R
S
K
P
A
S
V
I
T
S
A
G
I
Y
K
Zebra Danio
Brachydanio rerio
NP_571586
577
64904
H547
T
D
R
T
C
R
K
H
C
S
T
S
H
C
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P18537
581
64829
V550
L
V
G
V
T
S
S
V
W
L
Y
S
S
K
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790565
610
68431
K575
P
N
G
G
T
P
N
K
E
N
R
P
T
T
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
71.5
61.7
96.6
N.A.
95.6
47.8
N.A.
60
63.7
62.9
71.4
N.A.
36.7
N.A.
N.A.
47
Protein Similarity:
100
74.2
75.6
97.3
N.A.
96.7
64.3
N.A.
71.5
78.3
77.5
81.3
N.A.
53.6
N.A.
N.A.
64.2
P-Site Identity:
100
100
13.3
86.6
N.A.
86.6
0
N.A.
20
13.3
13.3
0
N.A.
0
N.A.
N.A.
20
P-Site Similarity:
100
100
26.6
86.6
N.A.
86.6
46.6
N.A.
33.3
26.6
33.3
0
N.A.
13.3
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
34
9
0
59
0
0
0
9
0
17
0
0
0
0
% A
% Cys:
0
0
34
0
9
0
0
0
9
0
0
9
0
9
34
% C
% Asp:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
17
9
0
9
34
17
0
42
9
67
0
0
0
% G
% His:
0
0
0
0
0
0
9
9
0
0
0
0
9
34
9
% H
% Ile:
0
0
0
0
0
0
0
34
0
0
0
0
34
0
0
% I
% Lys:
34
0
34
9
0
0
9
9
0
0
9
0
0
9
34
% K
% Leu:
9
0
0
0
0
9
0
0
0
9
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
9
0
0
0
0
9
0
0
9
0
0
0
9
0
% N
% Pro:
9
0
0
34
0
34
0
0
0
0
0
9
0
0
9
% P
% Gln:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% Q
% Arg:
34
25
9
34
0
9
0
0
0
0
42
0
0
0
9
% R
% Ser:
0
17
0
0
0
42
9
17
0
34
9
17
17
0
0
% S
% Thr:
9
0
0
9
34
0
0
9
25
0
9
0
42
9
9
% T
% Val:
0
9
0
9
0
0
34
9
0
0
0
0
0
0
0
% V
% Trp:
9
0
0
0
0
0
0
0
17
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
34
0
9
0
0
34
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _