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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FZD9
All Species:
9.09
Human Site:
S498
Identified Species:
18.18
UniProt:
O00144
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00144
NP_003499.1
591
64466
S498
P
G
G
R
R
D
C
S
L
P
G
G
S
V
P
Chimpanzee
Pan troglodytes
XP_527779
484
53212
G394
R
R
D
C
S
L
P
G
G
S
V
P
T
V
A
Rhesus Macaque
Macaca mulatta
XP_001109720
567
63652
C478
N
Q
T
K
T
L
D
C
L
M
A
A
S
I
P
Dog
Lupus familis
XP_546927
594
64924
S501
P
G
G
R
R
D
C
S
L
P
G
G
S
V
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9R216
592
64976
S499
P
G
G
R
R
D
C
S
L
P
G
G
S
V
P
Rat
Rattus norvegicus
Q9QZH0
538
60336
L444
K
I
G
V
F
S
V
L
Y
T
V
P
A
T
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520614
537
59681
C448
N
R
T
G
D
L
D
C
T
M
S
G
S
I
P
Chicken
Gallus gallus
Q9PWH2
585
65927
C496
N
Q
T
K
N
L
D
C
M
M
N
N
S
I
P
Frog
Xenopus laevis
Q9DEB5
586
65560
C497
S
Q
T
K
T
L
D
C
T
M
T
S
S
I
P
Zebra Danio
Brachydanio rerio
NP_571586
577
64904
R488
C
T
T
F
P
G
R
R
N
E
D
C
S
L
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P18537
581
64829
G488
L
P
A
V
G
L
L
G
C
L
F
Y
E
Y
Y
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790565
610
68431
A496
P
E
Q
G
G
G
C
A
P
M
D
Y
S
I
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
71.5
61.7
96.6
N.A.
95.6
47.8
N.A.
60
63.7
62.9
71.4
N.A.
36.7
N.A.
N.A.
47
Protein Similarity:
100
74.2
75.6
97.3
N.A.
96.7
64.3
N.A.
71.5
78.3
77.5
81.3
N.A.
53.6
N.A.
N.A.
64.2
P-Site Identity:
100
6.6
20
100
N.A.
100
6.6
N.A.
20
13.3
13.3
6.6
N.A.
0
N.A.
N.A.
26.6
P-Site Similarity:
100
13.3
33.3
100
N.A.
100
13.3
N.A.
26.6
33.3
26.6
13.3
N.A.
0
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
0
0
0
9
0
0
9
9
9
0
9
% A
% Cys:
9
0
0
9
0
0
34
34
9
0
0
9
0
0
9
% C
% Asp:
0
0
9
0
9
25
34
0
0
0
17
0
0
0
9
% D
% Glu:
0
9
0
0
0
0
0
0
0
9
0
0
9
0
0
% E
% Phe:
0
0
0
9
9
0
0
0
0
0
9
0
0
0
0
% F
% Gly:
0
25
34
17
17
17
0
17
9
0
25
34
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
9
0
0
0
0
0
0
0
0
0
0
0
42
0
% I
% Lys:
9
0
0
25
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
9
0
0
0
0
50
9
9
34
9
0
0
0
9
0
% L
% Met:
0
0
0
0
0
0
0
0
9
42
0
0
0
0
0
% M
% Asn:
25
0
0
0
9
0
0
0
9
0
9
9
0
0
0
% N
% Pro:
34
9
0
0
9
0
9
0
9
25
0
17
0
0
67
% P
% Gln:
0
25
9
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
9
17
0
25
25
0
9
9
0
0
0
0
0
0
0
% R
% Ser:
9
0
0
0
9
9
0
25
0
9
9
9
75
0
0
% S
% Thr:
0
9
42
0
17
0
0
0
17
9
9
0
9
9
0
% T
% Val:
0
0
0
17
0
0
9
0
0
0
17
0
0
34
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
9
0
0
17
0
9
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _