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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FZD9 All Species: 24.24
Human Site: S224 Identified Species: 48.48
UniProt: O00144 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O00144 NP_003499.1 591 64466 S224 P G V E V F W S R R D K D F A
Chimpanzee Pan troglodytes XP_527779 484 53212 V126 R D K D F A L V W M A V W S A
Rhesus Macaque Macaca mulatta XP_001109720 567 63652 S206 P G V D V Y W S R E D K R F A
Dog Lupus familis XP_546927 594 64924 S227 P G V E V F W S R R D K D F A
Cat Felis silvestris
Mouse Mus musculus Q9R216 592 64976 S225 P G V E V F W S R R D K D F A
Rat Rattus norvegicus Q9QZH0 538 60336 F149 D S L N C S K F P P Q N D H N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520614 537 59681 G176 P G V D V Y W G R D D K R F A
Chicken Gallus gallus Q9PWH2 585 65927 S224 P G V D V Y W S K D D K Q F A
Frog Xenopus laevis Q9DEB5 586 65560 S225 S S V D V Y W S K D D K K F A
Zebra Danio Brachydanio rerio NP_571586 577 64904 S220 S A V D V F W S R Q D K D F A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P18537 581 64829 E218 T P L G M G Y E L K V G G K D
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_790565 610 68431 Q222 C D V D V Y F Q R S D K E F T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 71.5 61.7 96.6 N.A. 95.6 47.8 N.A. 60 63.7 62.9 71.4 N.A. 36.7 N.A. N.A. 47
Protein Similarity: 100 74.2 75.6 97.3 N.A. 96.7 64.3 N.A. 71.5 78.3 77.5 81.3 N.A. 53.6 N.A. N.A. 64.2
P-Site Identity: 100 6.6 73.3 100 N.A. 100 6.6 N.A. 66.6 66.6 53.3 73.3 N.A. 0 N.A. N.A. 40
P-Site Similarity: 100 13.3 86.6 100 N.A. 100 13.3 N.A. 80 86.6 73.3 86.6 N.A. 26.6 N.A. N.A. 66.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 0 0 0 9 0 0 0 0 9 0 0 0 75 % A
% Cys: 9 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 9 17 0 59 0 0 0 0 0 25 75 0 42 0 9 % D
% Glu: 0 0 0 25 0 0 0 9 0 9 0 0 9 0 0 % E
% Phe: 0 0 0 0 9 34 9 9 0 0 0 0 0 75 0 % F
% Gly: 0 50 0 9 0 9 0 9 0 0 0 9 9 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 9 0 0 0 9 0 17 9 0 75 9 9 0 % K
% Leu: 0 0 17 0 0 0 9 0 9 0 0 0 0 0 0 % L
% Met: 0 0 0 0 9 0 0 0 0 9 0 0 0 0 0 % M
% Asn: 0 0 0 9 0 0 0 0 0 0 0 9 0 0 9 % N
% Pro: 50 9 0 0 0 0 0 0 9 9 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 9 0 9 9 0 9 0 0 % Q
% Arg: 9 0 0 0 0 0 0 0 59 25 0 0 17 0 0 % R
% Ser: 17 17 0 0 0 9 0 59 0 9 0 0 0 9 0 % S
% Thr: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % T
% Val: 0 0 75 0 75 0 0 9 0 0 9 9 0 0 0 % V
% Trp: 0 0 0 0 0 0 67 0 9 0 0 0 9 0 0 % W
% Tyr: 0 0 0 0 0 42 9 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _