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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FER1L4 All Species: 12.42
Human Site: S746 Identified Species: 30.37
UniProt: A9Z1Z3 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.22
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A9Z1Z3 NP_001034201 1794 200980 S746 P D L L P E P S A G L P S S L
Chimpanzee Pan troglodytes XP_525311 1967 220236 S949 P D L L P E P S A G L P S S L
Rhesus Macaque Macaca mulatta XP_001100421 2000 224900 L949 P D L L P E P L V G L P S S L
Dog Lupus familis XP_542977 1781 200452 S727 L D L L P E P S V G L P H H L
Cat Felis silvestris
Mouse Mus musculus A3KGK3 1992 223873 S952 M D L L P E P S S G L P Q S L
Rat Rattus norvegicus Q9ERC5 1993 226321 H960 A A Q G L G L H S F P P I S L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511652 1860 209863 S813 E T E Q T G T S E N P S F K L
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q5SPC5 1992 226210 Q953 A V K G I G I Q A V P P I S L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_393799 1896 219389 D898 V F L R N P W D K E E A D Y M
Nematode Worm Caenorhab. elegans Q17388 2034 235223 E956 E N K D P D S E D P R F R V Y
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 87.4 83.4 86.2 N.A. 74.5 34.5 N.A. 40.2 N.A. N.A. 34.4 N.A. N.A. 26.5 20.4 N.A.
Protein Similarity: 100 87.9 84.8 91.1 N.A. 80.6 51.9 N.A. 59.4 N.A. N.A. 52.6 N.A. N.A. 43 37.5 N.A.
P-Site Identity: 100 100 86.6 73.3 N.A. 80 20 N.A. 13.3 N.A. N.A. 26.6 N.A. N.A. 6.6 6.6 N.A.
P-Site Similarity: 100 100 86.6 73.3 N.A. 86.6 26.6 N.A. 13.3 N.A. N.A. 26.6 N.A. N.A. 13.3 20 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 20 10 0 0 0 0 0 0 30 0 0 10 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 50 0 10 0 10 0 10 10 0 0 0 10 0 0 % D
% Glu: 20 0 10 0 0 50 0 10 10 10 10 0 0 0 0 % E
% Phe: 0 10 0 0 0 0 0 0 0 10 0 10 10 0 0 % F
% Gly: 0 0 0 20 0 30 0 0 0 50 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 10 0 0 0 0 10 10 0 % H
% Ile: 0 0 0 0 10 0 10 0 0 0 0 0 20 0 0 % I
% Lys: 0 0 20 0 0 0 0 0 10 0 0 0 0 10 0 % K
% Leu: 10 0 60 50 10 0 10 10 0 0 50 0 0 0 80 % L
% Met: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % M
% Asn: 0 10 0 0 10 0 0 0 0 10 0 0 0 0 0 % N
% Pro: 30 0 0 0 60 10 50 0 0 10 30 70 0 0 0 % P
% Gln: 0 0 10 10 0 0 0 10 0 0 0 0 10 0 0 % Q
% Arg: 0 0 0 10 0 0 0 0 0 0 10 0 10 0 0 % R
% Ser: 0 0 0 0 0 0 10 50 20 0 0 10 30 60 0 % S
% Thr: 0 10 0 0 10 0 10 0 0 0 0 0 0 0 0 % T
% Val: 10 10 0 0 0 0 0 0 20 10 0 0 0 10 0 % V
% Trp: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _