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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FAM149B2 All Species: 15.15
Human Site: S234 Identified Species: 37.04
UniProt: A8MUB0 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.22
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A8MUB0 NP_775483 301 33751 S234 S P S P M S L S R N N L L P P
Chimpanzee Pan troglodytes XP_510611 582 64647 S467 S P S P M P L S R N N L L P P
Rhesus Macaque Macaca mulatta XP_001103228 582 64347 S467 S P S P M P L S R N N L L P P
Dog Lupus familis XP_852325 678 75177 S482 S P S P M P M S R N N L L P P
Cat Felis silvestris
Mouse Mus musculus Q6NSV7 578 63195 G467 S P S P M T L G R N N L L P P
Rat Rattus norvegicus Q5PQL8 482 53199 G371 S P S P M T M G R N N L L P P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508343 669 74373 P590 S H S G T P R P K E D V V R G
Chicken Gallus gallus XP_421523 584 64377 R466 P S P L L L N R N S L L P P I
Frog Xenopus laevis
Zebra Danio Brachydanio rerio A1L253 644 72042 R486 S P P M H L S R N T L L P P I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001203466 580 64210 S435 V S P P R Q F S R N T M L P P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 46 45.8 35.8 N.A. 40.1 48.5 N.A. 29.1 28.2 N.A. 21.4 N.A. N.A. N.A. N.A. 22.7
Protein Similarity: 100 47.5 48.4 39.2 N.A. 45.1 53.7 N.A. 35.7 38.8 N.A. 33.3 N.A. N.A. N.A. N.A. 34.3
P-Site Identity: 100 93.3 93.3 86.6 N.A. 86.6 80 N.A. 13.3 13.3 N.A. 26.6 N.A. N.A. N.A. N.A. 46.6
P-Site Similarity: 100 93.3 93.3 93.3 N.A. 93.3 93.3 N.A. 40 26.6 N.A. 26.6 N.A. N.A. N.A. N.A. 53.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 10 0 0 0 20 0 0 0 0 0 0 10 % G
% His: 0 10 0 0 10 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 20 % I
% Lys: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % K
% Leu: 0 0 0 10 10 20 40 0 0 0 20 80 70 0 0 % L
% Met: 0 0 0 10 60 0 20 0 0 0 0 10 0 0 0 % M
% Asn: 0 0 0 0 0 0 10 0 20 70 60 0 0 0 0 % N
% Pro: 10 70 30 70 0 40 0 10 0 0 0 0 20 90 70 % P
% Gln: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 10 0 10 20 70 0 0 0 0 10 0 % R
% Ser: 80 20 70 0 0 10 10 50 0 10 0 0 0 0 0 % S
% Thr: 0 0 0 0 10 20 0 0 0 10 10 0 0 0 0 % T
% Val: 10 0 0 0 0 0 0 0 0 0 0 10 10 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _