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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FAM166B All Species: 11.82
Human Site: S166 Identified Species: 23.64
UniProt: A8MTA8 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A8MTA8 NP_001093421.1 275 30575 S166 L E V V E Q A S P Y S M D D R
Chimpanzee Pan troglodytes XP_520557 240 26790 L132 E K Q G S E E L P K E A K G R
Rhesus Macaque Macaca mulatta XP_001085649 338 36855 S229 Q G L L S Q A S P Y S M D D R
Dog Lupus familis XP_538716 252 28221 E143 A N G T K D V E K D Q E P K L
Cat Felis silvestris
Mouse Mus musculus A2AIP0 273 30233 Y165 E L A H A S P Y S M D D T D P
Rat Rattus norvegicus Q4QR77 321 36975 L206 D V G R Y Q R L P Q L D H P N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521092 133 14658 T25 A Q A L S E F T H Q G V R P R
Chicken Gallus gallus
Frog Xenopus laevis A9JS51 311 35470 P202 Y Y M E E E N P N K Y F I S G
Zebra Danio Brachydanio rerio A2RRW4 299 33254 S177 D P W K P P G S P Y F M E D S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q7JRP4 323 36804 S191 L C Y S K F T S P H F L E D E
Honey Bee Apis mellifera XP_623747 312 35435 S194 A P R D H A P S P Y F M D N A
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_786484 328 37388 V210 G F I P R Q G V T E L G L G A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 85 76.3 73 N.A. 75.2 25.5 N.A. 26.9 N.A. 42.4 37.1 N.A. 28.4 28.5 N.A. 24
Protein Similarity: 100 86.5 77.8 78.1 N.A. 83.2 38 N.A. 34.9 N.A. 56.2 51.1 N.A. 44.2 46.4 N.A. 42
P-Site Identity: 100 13.3 66.6 0 N.A. 6.6 13.3 N.A. 6.6 N.A. 6.6 33.3 N.A. 26.6 33.3 N.A. 6.6
P-Site Similarity: 100 26.6 80 6.6 N.A. 6.6 13.3 N.A. 40 N.A. 20 40 N.A. 53.3 40 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 25 0 17 0 9 9 17 0 0 0 0 9 0 0 17 % A
% Cys: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 17 0 0 9 0 9 0 0 0 9 9 17 25 42 0 % D
% Glu: 17 9 0 9 17 25 9 9 0 9 9 9 17 0 9 % E
% Phe: 0 9 0 0 0 9 9 0 0 0 25 9 0 0 0 % F
% Gly: 9 9 17 9 0 0 17 0 0 0 9 9 0 17 9 % G
% His: 0 0 0 9 9 0 0 0 9 9 0 0 9 0 0 % H
% Ile: 0 0 9 0 0 0 0 0 0 0 0 0 9 0 0 % I
% Lys: 0 9 0 9 17 0 0 0 9 17 0 0 9 9 0 % K
% Leu: 17 9 9 17 0 0 0 17 0 0 17 9 9 0 9 % L
% Met: 0 0 9 0 0 0 0 0 0 9 0 34 0 0 0 % M
% Asn: 0 9 0 0 0 0 9 0 9 0 0 0 0 9 9 % N
% Pro: 0 17 0 9 9 9 17 9 59 0 0 0 9 17 9 % P
% Gln: 9 9 9 0 0 34 0 0 0 17 9 0 0 0 0 % Q
% Arg: 0 0 9 9 9 0 9 0 0 0 0 0 9 0 34 % R
% Ser: 0 0 0 9 25 9 0 42 9 0 17 0 0 9 9 % S
% Thr: 0 0 0 9 0 0 9 9 9 0 0 0 9 0 0 % T
% Val: 0 9 9 9 0 0 9 9 0 0 0 9 0 0 0 % V
% Trp: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 9 9 9 0 9 0 0 9 0 34 9 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _