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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: All Species: 13.64
Human Site: S536 Identified Species: 27.27
UniProt: A8MT19 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A8MT19 NP_149094 583 65945 S536 Q K I S K K L S F L S W G T N
Chimpanzee Pan troglodytes XP_001152684 686 76936 S639 K K I S K K L S F L S W G T N
Rhesus Macaque Macaca mulatta XP_001107427 591 66623 V545 Y I V S I Q L V D C K W L T V
Dog Lupus familis XP_539197 623 67119 E557 C K W W K H A E V V A Q L K G
Cat Felis silvestris
Mouse Mus musculus Q8BWR8 686 76939 S639 K K I S K K L S F L S W G T S
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509093 779 87744 S732 K K V S K K L S F L S W G T N
Chicken Gallus gallus XP_414133 679 76430 L633 A K K A P L K L P F L S W G T
Frog Xenopus laevis Q6DJJ6 683 77116 L636 T Q K A T K K L S F L S W G F
Zebra Danio Brachydanio rerio Q6TNR1 683 77039 A636 N P K S R K V A K K P S F L S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_511168 718 80809 G657 L K P L S S K G S L S T L S A
Honey Bee Apis mellifera XP_001120267 660 74505 G614 V S A S S S S G I S S G Q P S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_785878 687 77731 L617 S M T S D S S L E R Q Q P P R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 77.9 71.9 29.7 N.A. 67.1 N.A. N.A. 54.5 56.2 49.6 45.2 N.A. 26.4 33.7 N.A. 31
Protein Similarity: 100 79.7 74.6 45.2 N.A. 73.7 N.A. N.A. 62.9 68 62.8 62.2 N.A. 41.9 50.9 N.A. 48.3
P-Site Identity: 100 93.3 26.6 13.3 N.A. 86.6 N.A. N.A. 86.6 6.6 6.6 13.3 N.A. 20 13.3 N.A. 6.6
P-Site Similarity: 100 100 40 26.6 N.A. 100 N.A. N.A. 100 13.3 20 40 N.A. 26.6 20 N.A. 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 9 17 0 0 9 9 0 0 9 0 0 0 9 % A
% Cys: 9 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % C
% Asp: 0 0 0 0 9 0 0 0 9 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 9 9 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 34 17 0 0 9 0 9 % F
% Gly: 0 0 0 0 0 0 0 17 0 0 0 9 34 17 9 % G
% His: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 9 25 0 9 0 0 0 9 0 0 0 0 0 0 % I
% Lys: 25 59 25 0 42 50 25 0 9 9 9 0 0 9 0 % K
% Leu: 9 0 0 9 0 9 42 25 0 42 17 0 25 9 0 % L
% Met: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 25 % N
% Pro: 0 9 9 0 9 0 0 0 9 0 9 0 9 17 0 % P
% Gln: 9 9 0 0 0 9 0 0 0 0 9 17 9 0 0 % Q
% Arg: 0 0 0 0 9 0 0 0 0 9 0 0 0 0 9 % R
% Ser: 9 9 0 67 17 25 17 34 17 9 50 25 0 9 25 % S
% Thr: 9 0 9 0 9 0 0 0 0 0 0 9 0 42 9 % T
% Val: 9 0 17 0 0 0 9 9 9 9 0 0 0 0 9 % V
% Trp: 0 0 9 9 0 0 0 0 0 0 0 42 17 0 0 % W
% Tyr: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _