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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: All Species: 23.03
Human Site: S595 Identified Species: 38.97
UniProt: A8MPP1 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A8MPP1 NP_085911 907 101811 S595 R Q G S L S E S T L K F L L L
Chimpanzee Pan troglodytes XP_520821 925 103112 S612 R Q G S L S Q S T L K F L L L
Rhesus Macaque Macaca mulatta XP_001114510 906 101461 S593 R Q G S L S Q S T L K F L L L
Dog Lupus familis XP_543872 907 102087 S594 R Q G S L S Q S S L K F L L L
Cat Felis silvestris
Mouse Mus musculus Q6AXC6 880 98710 Q564 N R Q G S V G Q S S L K F L L
Rat Rattus norvegicus XP_001070646 845 94905 S530 R Q G S V G Q S S L K F L L L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517598 930 104705 S624 H Q S S L S L S S L K F L L L
Chicken Gallus gallus XP_416375 940 105739 Q624 G R V I L N R Q G T I G Q S S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001007320 890 100643 A571 R I V I Q R Q A C V A Q S S L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_569898 861 96577 Y567 P V G G T L K Y I L L D P A E
Honey Bee Apis mellifera XP_001121183 769 88327 E519 C D H V I P K E N I I C N I I
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_792082 780 88384 V523 L E F S C G H V I P P E H L L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P22516 861 98787 G583 A K C V V L A G G T M E P M S
Red Bread Mold Neurospora crassa A7UXD4 1073 119198 S698 S P T H A F S S I A E S A R A
Conservation
Percent
Protein Identity: 100 93.9 96.2 83.1 N.A. 76.9 71.7 N.A. 73.5 68.1 N.A. 59.9 N.A. 39.2 38.1 N.A. 46.6
Protein Similarity: 100 95.6 97.4 90.1 N.A. 84.9 80.3 N.A. 83.5 80.3 N.A. 76.1 N.A. 56.1 56.1 N.A. 62.6
P-Site Identity: 100 93.3 93.3 86.6 N.A. 13.3 73.3 N.A. 73.3 6.6 N.A. 13.3 N.A. 13.3 0 N.A. 20
P-Site Similarity: 100 100 100 100 N.A. 26.6 93.3 N.A. 80 20 N.A. 33.3 N.A. 20 33.3 N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 32.4 28.5
Protein Similarity: N.A. N.A. N.A. N.A. 51.1 44.7
P-Site Identity: N.A. N.A. N.A. N.A. 0 6.6
P-Site Similarity: N.A. N.A. N.A. N.A. 20 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 0 8 0 8 8 0 8 8 0 8 8 8 % A
% Cys: 8 0 8 0 8 0 0 0 8 0 0 8 0 0 0 % C
% Asp: 0 8 0 0 0 0 0 0 0 0 0 8 0 0 0 % D
% Glu: 0 8 0 0 0 0 8 8 0 0 8 15 0 0 8 % E
% Phe: 0 0 8 0 0 8 0 0 0 0 0 43 8 0 0 % F
% Gly: 8 0 43 15 0 15 8 8 15 0 0 8 0 0 0 % G
% His: 8 0 8 8 0 0 8 0 0 0 0 0 8 0 0 % H
% Ile: 0 8 0 15 8 0 0 0 22 8 15 0 0 8 8 % I
% Lys: 0 8 0 0 0 0 15 0 0 0 43 8 0 0 0 % K
% Leu: 8 0 0 0 43 15 8 0 0 50 15 0 43 58 65 % L
% Met: 0 0 0 0 0 0 0 0 0 0 8 0 0 8 0 % M
% Asn: 8 0 0 0 0 8 0 0 8 0 0 0 8 0 0 % N
% Pro: 8 8 0 0 0 8 0 0 0 8 8 0 15 0 0 % P
% Gln: 0 43 8 0 8 0 36 15 0 0 0 8 8 0 0 % Q
% Arg: 43 15 0 0 0 8 8 0 0 0 0 0 0 8 0 % R
% Ser: 8 0 8 50 8 36 8 50 29 8 0 8 8 15 15 % S
% Thr: 0 0 8 0 8 0 0 0 22 15 0 0 0 0 0 % T
% Val: 0 8 15 15 15 8 0 8 0 8 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _