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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: All Species: 20.61
Human Site: S563 Identified Species: 34.87
UniProt: A8MPP1 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A8MPP1 NP_085911 907 101811 S563 A S V P Q P A S P L M H I E G
Chimpanzee Pan troglodytes XP_520821 925 103112 S580 A S T P R P A S P L M H I E G
Rhesus Macaque Macaca mulatta XP_001114510 906 101461 S561 A S A P R P A S P L M H I E G
Dog Lupus familis XP_543872 907 102087 S562 A R V P R P A S P L M H I E S
Cat Felis silvestris
Mouse Mus musculus Q6AXC6 880 98710 A532 Q A V A L R P A S P L M H I E
Rat Rattus norvegicus XP_001070646 845 94905 S498 A V A L R P A S P L M H I E A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517598 930 104705 S592 N G P P R P A S P L M H I E G
Chicken Gallus gallus XP_416375 940 105739 D592 P P V E A D S D Q L R A A S P
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001007320 890 100643 K539 Q Q M A V E D K P I M A S P M
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_569898 861 96577 S535 P V E E V A P S P I R P L L A
Honey Bee Apis mellifera XP_001121183 769 88327 A487 I L A G G T M A P M N E F I E
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_792082 780 88384 G491 A R A I I V A G G T M Q P V E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P22516 861 98787 F551 L T S E G Q F F F E K N Y S I
Red Bread Mold Neurospora crassa A7UXD4 1073 119198 G666 L T N L S S E G R I F Y E K I
Conservation
Percent
Protein Identity: 100 93.9 96.2 83.1 N.A. 76.9 71.7 N.A. 73.5 68.1 N.A. 59.9 N.A. 39.2 38.1 N.A. 46.6
Protein Similarity: 100 95.6 97.4 90.1 N.A. 84.9 80.3 N.A. 83.5 80.3 N.A. 76.1 N.A. 56.1 56.1 N.A. 62.6
P-Site Identity: 100 86.6 86.6 80 N.A. 6.6 66.6 N.A. 73.3 13.3 N.A. 13.3 N.A. 13.3 6.6 N.A. 20
P-Site Similarity: 100 93.3 93.3 86.6 N.A. 26.6 73.3 N.A. 80 20 N.A. 26.6 N.A. 26.6 20 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. 32.4 28.5
Protein Similarity: N.A. N.A. N.A. N.A. 51.1 44.7
P-Site Identity: N.A. N.A. N.A. N.A. 0 0
P-Site Similarity: N.A. N.A. N.A. N.A. 13.3 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 43 8 29 15 8 8 50 15 0 0 0 15 8 0 15 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 8 8 8 0 0 0 0 0 0 0 % D
% Glu: 0 0 8 22 0 8 8 0 0 8 0 8 8 43 22 % E
% Phe: 0 0 0 0 0 0 8 8 8 0 8 0 8 0 0 % F
% Gly: 0 8 0 8 15 0 0 15 8 0 0 0 0 0 29 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 43 8 0 0 % H
% Ile: 8 0 0 8 8 0 0 0 0 22 0 0 43 15 15 % I
% Lys: 0 0 0 0 0 0 0 8 0 0 8 0 0 8 0 % K
% Leu: 15 8 0 15 8 0 0 0 0 50 8 0 8 8 0 % L
% Met: 0 0 8 0 0 0 8 0 0 8 58 8 0 0 8 % M
% Asn: 8 0 8 0 0 0 0 0 0 0 8 8 0 0 0 % N
% Pro: 15 8 8 36 0 43 15 0 65 8 0 8 8 8 8 % P
% Gln: 15 8 0 0 8 8 0 0 8 0 0 8 0 0 0 % Q
% Arg: 0 15 0 0 36 8 0 0 8 0 15 0 0 0 0 % R
% Ser: 0 22 8 0 8 8 8 50 8 0 0 0 8 15 8 % S
% Thr: 0 15 8 0 0 8 0 0 0 8 0 0 0 0 0 % T
% Val: 0 15 29 0 15 8 0 0 0 0 0 0 0 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 8 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _