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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
All Species:
10
Human Site:
S557
Identified Species:
16.92
UniProt:
A8MPP1
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A8MPP1
NP_085911
907
101811
S557
P
A
D
E
S
Q
A
S
V
P
Q
P
A
S
P
Chimpanzee
Pan troglodytes
XP_520821
925
103112
S574
P
A
D
E
S
Q
A
S
T
P
R
P
A
S
P
Rhesus Macaque
Macaca mulatta
XP_001114510
906
101461
S555
P
A
D
E
S
Q
A
S
A
P
R
P
A
S
P
Dog
Lupus familis
XP_543872
907
102087
R556
P
V
E
D
G
E
A
R
V
P
R
P
A
S
P
Cat
Felis silvestris
Mouse
Mus musculus
Q6AXC6
880
98710
A526
D
S
P
E
E
G
Q
A
V
A
L
R
P
A
S
Rat
Rattus norvegicus
XP_001070646
845
94905
V492
S
L
E
E
G
Q
A
V
A
L
R
P
A
S
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517598
930
104705
G586
P
T
E
E
G
E
N
G
P
P
R
P
A
S
P
Chicken
Gallus gallus
XP_416375
940
105739
P586
E
G
P
L
Q
S
P
P
V
E
A
D
S
D
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001007320
890
100643
Q533
P
T
D
V
S
E
Q
Q
M
A
V
E
D
K
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_569898
861
96577
V529
Q
K
P
T
K
K
P
V
E
E
V
A
P
S
P
Honey Bee
Apis mellifera
XP_001121183
769
88327
L481
R
D
A
R
A
V
I
L
A
G
G
T
M
A
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_792082
780
88384
R485
T
D
V
V
K
E
A
R
A
I
I
V
A
G
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P22516
861
98787
T545
L
Y
C
L
T
N
L
T
S
E
G
Q
F
F
F
Red Bread Mold
Neurospora crassa
A7UXD4
1073
119198
T660
C
S
F
L
T
A
L
T
N
L
S
S
E
G
R
Conservation
Percent
Protein Identity:
100
93.9
96.2
83.1
N.A.
76.9
71.7
N.A.
73.5
68.1
N.A.
59.9
N.A.
39.2
38.1
N.A.
46.6
Protein Similarity:
100
95.6
97.4
90.1
N.A.
84.9
80.3
N.A.
83.5
80.3
N.A.
76.1
N.A.
56.1
56.1
N.A.
62.6
P-Site Identity:
100
86.6
86.6
53.3
N.A.
13.3
46.6
N.A.
46.6
6.6
N.A.
26.6
N.A.
13.3
6.6
N.A.
13.3
P-Site Similarity:
100
93.3
93.3
80
N.A.
33.3
60
N.A.
66.6
13.3
N.A.
40
N.A.
20
20
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
32.4
28.5
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
51.1
44.7
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
22
8
0
8
8
43
8
29
15
8
8
50
15
0
% A
% Cys:
8
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
15
29
8
0
0
0
0
0
0
0
8
8
8
0
% D
% Glu:
8
0
22
43
8
29
0
0
8
22
0
8
8
0
0
% E
% Phe:
0
0
8
0
0
0
0
0
0
0
0
0
8
8
8
% F
% Gly:
0
8
0
0
22
8
0
8
0
8
15
0
0
15
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
8
0
0
8
8
0
0
0
0
% I
% Lys:
0
8
0
0
15
8
0
0
0
0
0
0
0
8
0
% K
% Leu:
8
8
0
22
0
0
15
8
0
15
8
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
8
0
0
0
8
0
0
% M
% Asn:
0
0
0
0
0
8
8
0
8
0
0
0
0
0
0
% N
% Pro:
43
0
22
0
0
0
15
8
8
36
0
43
15
0
65
% P
% Gln:
8
0
0
0
8
29
15
8
0
0
8
8
0
0
8
% Q
% Arg:
8
0
0
8
0
0
0
15
0
0
36
8
0
0
8
% R
% Ser:
8
15
0
0
29
8
0
22
8
0
8
8
8
50
8
% S
% Thr:
8
15
0
8
15
0
0
15
8
0
0
8
0
0
0
% T
% Val:
0
8
8
15
0
8
0
15
29
0
15
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _