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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: All Species: 25.45
Human Site: S261 Identified Species: 43.08
UniProt: A8MPP1 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A8MPP1 NP_085911 907 101811 S261 G K D V R L V S L G S R Q N L
Chimpanzee Pan troglodytes XP_520821 925 103112 S278 G K D V R L V S L G S R Q N L
Rhesus Macaque Macaca mulatta XP_001114510 906 101461 S259 G K D V R L V S L G S R Q N L
Dog Lupus familis XP_543872 907 102087 S259 G K D T R L V S L G S R Q N L
Cat Felis silvestris
Mouse Mus musculus Q6AXC6 880 98710 S231 G K E T R L V S L G S R Q T L
Rat Rattus norvegicus XP_001070646 845 94905 R237 G E D K P K R R R Q K M Q A S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517598 930 104705 S276 G K E T R L A S L G S R Q S L
Chicken Gallus gallus XP_416375 940 105739 S292 G K D T R L V S L G S R Q N L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001007320 890 100643 N238 G D A V R L V N L G S R Q N L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_569898 861 96577 M242 K L K H V G L M N E R C L D M
Honey Bee Apis mellifera XP_001121183 769 88327 E229 L I Q I Q D I E E I V Q K G E
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_792082 780 88384 V233 Y Y G T R Y A V P N A Q L V V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P22516 861 98787 P272 D E K V K Y L P L A S K K Q L
Red Bread Mold Neurospora crassa A7UXD4 1073 119198 P380 K E I V K Q I P L S S R Q K L
Conservation
Percent
Protein Identity: 100 93.9 96.2 83.1 N.A. 76.9 71.7 N.A. 73.5 68.1 N.A. 59.9 N.A. 39.2 38.1 N.A. 46.6
Protein Similarity: 100 95.6 97.4 90.1 N.A. 84.9 80.3 N.A. 83.5 80.3 N.A. 76.1 N.A. 56.1 56.1 N.A. 62.6
P-Site Identity: 100 100 100 93.3 N.A. 80 20 N.A. 73.3 93.3 N.A. 80 N.A. 0 0 N.A. 6.6
P-Site Similarity: 100 100 100 93.3 N.A. 86.6 26.6 N.A. 86.6 93.3 N.A. 86.6 N.A. 20 33.3 N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 32.4 28.5
Protein Similarity: N.A. N.A. N.A. N.A. 51.1 44.7
P-Site Identity: N.A. N.A. N.A. N.A. 26.6 40
P-Site Similarity: N.A. N.A. N.A. N.A. 60 60
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 0 0 0 15 0 0 8 8 0 0 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % C
% Asp: 8 8 43 0 0 8 0 0 0 0 0 0 0 8 0 % D
% Glu: 0 22 15 0 0 0 0 8 8 8 0 0 0 0 8 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 65 0 8 0 0 8 0 0 0 58 0 0 0 8 0 % G
% His: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 8 8 8 0 0 15 0 0 8 0 0 0 0 0 % I
% Lys: 15 50 15 8 15 8 0 0 0 0 8 8 15 8 0 % K
% Leu: 8 8 0 0 0 58 15 0 72 0 0 0 15 0 72 % L
% Met: 0 0 0 0 0 0 0 8 0 0 0 8 0 0 8 % M
% Asn: 0 0 0 0 0 0 0 8 8 8 0 0 0 43 0 % N
% Pro: 0 0 0 0 8 0 0 15 8 0 0 0 0 0 0 % P
% Gln: 0 0 8 0 8 8 0 0 0 8 0 15 72 8 0 % Q
% Arg: 0 0 0 0 65 0 8 8 8 0 8 65 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 50 0 8 72 0 0 8 8 % S
% Thr: 0 0 0 36 0 0 0 0 0 0 0 0 0 8 0 % T
% Val: 0 0 0 43 8 0 50 8 0 0 8 0 0 8 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 8 0 0 0 15 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _