Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: All Species: 29.39
Human Site: S251 Identified Species: 49.74
UniProt: A8MPP1 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A8MPP1 NP_085911 907 101811 S251 F V H E V K K S P F G K D V R
Chimpanzee Pan troglodytes XP_520821 925 103112 S268 F V H E V K K S P F G K D V R
Rhesus Macaque Macaca mulatta XP_001114510 906 101461 S249 F V H E V K K S P F G K D V R
Dog Lupus familis XP_543872 907 102087 S249 F V H E V Q R S P F G K D T R
Cat Felis silvestris
Mouse Mus musculus Q6AXC6 880 98710 S221 F V R E V L K S P F G K E T R
Rat Rattus norvegicus XP_001070646 845 94905 M227 Q R R K H K K M R I G E D K P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517598 930 104705 S266 F V H E V Q R S P F G K E T R
Chicken Gallus gallus XP_416375 940 105739 S282 F V H E V Q K S P F G K D T R
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001007320 890 100643 S228 F V H E V Q K S P Y G D A V R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_569898 861 96577 A232 Q Q L C G N P A V R K L K H V
Honey Bee Apis mellifera XP_001121183 769 88327 G219 G N Q D L L L G E I L I Q I Q
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_792082 780 88384 A223 K V G K E L K A C P Y Y G T R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P22516 861 98787 K262 F P S S F R D K V P D E K V K
Red Bread Mold Neurospora crassa A7UXD4 1073 119198 K370 P T P N P Q E K P A K E I V K
Conservation
Percent
Protein Identity: 100 93.9 96.2 83.1 N.A. 76.9 71.7 N.A. 73.5 68.1 N.A. 59.9 N.A. 39.2 38.1 N.A. 46.6
Protein Similarity: 100 95.6 97.4 90.1 N.A. 84.9 80.3 N.A. 83.5 80.3 N.A. 76.1 N.A. 56.1 56.1 N.A. 62.6
P-Site Identity: 100 100 100 80 N.A. 73.3 26.6 N.A. 73.3 86.6 N.A. 73.3 N.A. 0 0 N.A. 20
P-Site Similarity: 100 100 100 93.3 N.A. 80 40 N.A. 93.3 93.3 N.A. 86.6 N.A. 6.6 26.6 N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 32.4 28.5
Protein Similarity: N.A. N.A. N.A. N.A. 51.1 44.7
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 13.3
P-Site Similarity: N.A. N.A. N.A. N.A. 33.3 40
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 15 0 8 0 0 8 0 0 % A
% Cys: 0 0 0 8 0 0 0 0 8 0 0 0 0 0 0 % C
% Asp: 0 0 0 8 0 0 8 0 0 0 8 8 43 0 0 % D
% Glu: 0 0 0 58 8 0 8 0 8 0 0 22 15 0 0 % E
% Phe: 65 0 0 0 8 0 0 0 0 50 0 0 0 0 0 % F
% Gly: 8 0 8 0 8 0 0 8 0 0 65 0 8 0 0 % G
% His: 0 0 50 0 8 0 0 0 0 0 0 0 0 8 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 15 0 8 8 8 0 % I
% Lys: 8 0 0 15 0 29 58 15 0 0 15 50 15 8 15 % K
% Leu: 0 0 8 0 8 22 8 0 0 0 8 8 0 0 0 % L
% Met: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % M
% Asn: 0 8 0 8 0 8 0 0 0 0 0 0 0 0 0 % N
% Pro: 8 8 8 0 8 0 8 0 65 15 0 0 0 0 8 % P
% Gln: 15 8 8 0 0 36 0 0 0 0 0 0 8 0 8 % Q
% Arg: 0 8 15 0 0 8 15 0 8 8 0 0 0 0 65 % R
% Ser: 0 0 8 8 0 0 0 58 0 0 0 0 0 0 0 % S
% Thr: 0 8 0 0 0 0 0 0 0 0 0 0 0 36 0 % T
% Val: 0 65 0 0 58 0 0 0 15 0 0 0 0 43 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 8 8 8 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _