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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WASH1
All Species:
34.24
Human Site:
S44
Identified Species:
62.78
UniProt:
A8K0Z3
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A8K0Z3
NP_878908.3
465
50328
S44
L
Q
Y
L
Q
K
V
S
G
D
I
F
S
R
I
Chimpanzee
Pan troglodytes
XP_001145900
468
50425
S44
L
Q
Y
L
Q
K
V
S
G
D
I
F
G
R
I
Rhesus Macaque
Macaca mulatta
XP_001094494
443
47510
R35
S
Q
R
V
E
Q
S
R
N
Q
V
Q
A
I
G
Dog
Lupus familis
XP_543873
471
51116
S44
L
Q
Y
L
Q
K
V
S
G
D
I
F
S
R
I
Cat
Felis silvestris
Mouse
Mus musculus
Q8VDD8
475
51640
S44
L
Q
Y
L
Q
N
I
S
G
D
I
F
S
R
I
Rat
Rattus norvegicus
B2RYF7
475
51309
S44
L
Q
Y
L
Q
N
I
S
G
D
I
F
S
R
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517605
495
52719
S58
L
Q
Y
L
Q
K
V
S
G
D
I
F
S
R
I
Chicken
Gallus gallus
Q5ZKA6
476
51664
S44
L
Q
Y
L
Q
K
V
S
G
D
I
F
N
R
I
Frog
Xenopus laevis
Q5U4A3
472
51105
S41
L
Q
H
L
Q
T
V
S
N
D
I
F
S
R
I
Zebra Danio
Brachydanio rerio
A4IG59
481
52093
S44
L
Q
Y
L
E
M
I
S
T
D
I
F
T
R
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7JW27
499
53192
I40
L
D
C
L
H
K
T
I
N
S
I
F
E
R
I
Honey Bee
Apis mellifera
XP_001120697
464
51758
I41
V
N
Y
I
F
E
C
I
D
K
R
L
F
Q
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785243
480
51242
A35
L
E
Y
L
E
K
I
A
N
D
V
F
D
R
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.3
87.3
88.3
N.A.
82.3
82.1
N.A.
75.1
76.2
67.8
65.4
N.A.
29.8
25.8
N.A.
45.8
Protein Similarity:
100
97.2
89.8
92.1
N.A.
89
88
N.A.
82.2
84.2
78.3
76.5
N.A.
44.4
46.4
N.A.
62.7
P-Site Identity:
100
93.3
6.6
100
N.A.
86.6
86.6
N.A.
100
93.3
80
60
N.A.
46.6
6.6
N.A.
53.3
P-Site Similarity:
100
93.3
40
100
N.A.
93.3
93.3
N.A.
100
100
86.6
86.6
N.A.
46.6
33.3
N.A.
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
8
0
0
0
0
8
0
0
% A
% Cys:
0
0
8
0
0
0
8
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
0
0
0
0
0
8
77
0
0
8
0
0
% D
% Glu:
0
8
0
0
24
8
0
0
0
0
0
0
8
0
0
% E
% Phe:
0
0
0
0
8
0
0
0
0
0
0
85
8
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
54
0
0
0
8
0
8
% G
% His:
0
0
8
0
8
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
8
0
0
31
16
0
0
77
0
0
8
77
% I
% Lys:
0
0
0
0
0
54
0
0
0
8
0
0
0
0
0
% K
% Leu:
85
0
0
85
0
0
0
0
0
0
0
8
0
0
0
% L
% Met:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
0
16
0
0
31
0
0
0
8
0
8
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
77
0
0
62
8
0
0
0
8
0
8
0
8
0
% Q
% Arg:
0
0
8
0
0
0
0
8
0
0
8
0
0
85
0
% R
% Ser:
8
0
0
0
0
0
8
70
0
8
0
0
47
0
0
% S
% Thr:
0
0
0
0
0
8
8
0
8
0
0
0
8
0
0
% T
% Val:
8
0
0
8
0
0
47
0
0
0
16
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
77
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _