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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DHRS7C All Species: 28.48
Human Site: S227 Identified Species: 56.97
UniProt: A6NNS2 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A6NNS2 NP_001099041 312 34878 S227 V S P T F I R S Y H V Y P E Q
Chimpanzee Pan troglodytes XP_511842 308 34444 S223 V S P T F I R S Y H V Y P E Q
Rhesus Macaque Macaca mulatta XP_001118243 304 34063 S219 V S P T F V R S Y H V Y P E Q
Dog Lupus familis XP_536640 311 34533 S226 V S P T F I R S Y H V D P G Q
Cat Felis silvestris
Mouse Mus musculus Q8CHS7 311 34449 S226 V S P T F I R S Y R A S P E Q
Rat Rattus norvegicus Q5RJY4 325 35324 H241 V I S P G Y I H T N L S V N A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511308 544 58832 T461 V S P G Y I R T N L S L N A V
Chicken Gallus gallus XP_415576 311 34358 S226 V N P T F I C S Y H H Q P A P
Frog Xenopus laevis Q0IH28 323 35135 T226 V N P G Y I K T N L S L N A V
Zebra Danio Brachydanio rerio A8E5C5 324 35163 A226 I S H T F I N A G A E N A T P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9Y140 326 35725 T241 V S P G Y I R T Q L S L N A L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_793326 411 43892 T329 L S P S Y I K T N I S L S A L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.7 84.6 95.1 N.A. 91 39.3 N.A. 25.9 76.9 40.2 54.3 N.A. 32.2 N.A. N.A. 29.6
Protein Similarity: 100 98.7 86.5 97.4 N.A. 93.5 60 N.A. 38.9 87.8 61.2 71.9 N.A. 53.6 N.A. N.A. 45.9
P-Site Identity: 100 100 93.3 86.6 N.A. 80 6.6 N.A. 33.3 60 20 26.6 N.A. 33.3 N.A. N.A. 20
P-Site Similarity: 100 100 100 86.6 N.A. 80 20 N.A. 46.6 66.6 46.6 40 N.A. 46.6 N.A. N.A. 53.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 9 0 9 9 0 9 42 9 % A
% Cys: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 9 0 0 34 0 % E
% Phe: 0 0 0 0 59 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 25 9 0 0 0 9 0 0 0 0 9 0 % G
% His: 0 0 9 0 0 0 0 9 0 42 9 0 0 0 0 % H
% Ile: 9 9 0 0 0 84 9 0 0 9 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 17 0 0 0 0 0 0 0 0 % K
% Leu: 9 0 0 0 0 0 0 0 0 25 9 34 0 0 17 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 17 0 0 0 0 9 0 25 9 0 9 25 9 0 % N
% Pro: 0 0 84 9 0 0 0 0 0 0 0 0 50 0 17 % P
% Gln: 0 0 0 0 0 0 0 0 9 0 0 9 0 0 42 % Q
% Arg: 0 0 0 0 0 0 59 0 0 9 0 0 0 0 0 % R
% Ser: 0 75 9 9 0 0 0 50 0 0 34 17 9 0 0 % S
% Thr: 0 0 0 59 0 0 0 34 9 0 0 0 0 9 0 % T
% Val: 84 0 0 0 0 9 0 0 0 0 34 0 9 0 17 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 34 9 0 0 50 0 0 25 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _