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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CCT8L1
All Species:
22.73
Human Site:
S468
Identified Species:
50
UniProt:
A6NM43
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.3
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A6NM43
NP_055221
557
59514
S468
S
D
V
V
A
E
M
S
G
V
H
Q
G
G
N
Chimpanzee
Pan troglodytes
XP_525513
557
59397
S468
S
D
V
M
A
E
M
S
G
V
H
Q
G
G
N
Rhesus Macaque
Macaca mulatta
XP_001101969
548
59498
Y468
N
E
V
I
S
K
L
Y
A
V
H
Q
E
G
N
Dog
Lupus familis
XP_539926
555
58953
K468
S
E
V
M
A
E
M
K
G
A
H
Q
A
G
N
Cat
Felis silvestris
Mouse
Mus musculus
P42932
548
59537
Y468
N
E
V
I
S
K
L
Y
S
V
H
Q
E
G
N
Rat
Rattus norvegicus
Q6P502
545
60628
R467
I
R
L
L
T
S
L
R
A
K
H
T
Q
E
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q6EE31
548
59456
Y468
N
E
V
I
S
K
L
Y
A
V
H
Q
E
G
N
Frog
Xenopus laevis
P50143
547
60618
R466
I
R
I
L
T
S
L
R
A
K
H
T
Q
E
G
Zebra Danio
Brachydanio rerio
NP_957356
546
59283
Y468
N
E
L
I
S
K
L
Y
A
T
H
H
E
G
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610418
546
59415
Y468
T
E
I
V
N
Q
L
Y
L
A
H
N
N
E
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9N358
581
63437
Y501
T
E
T
L
T
K
L
Y
A
E
H
V
A
G
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.4
30.3
71.6
N.A.
30.3
23.7
N.A.
N.A.
29.9
24.2
30.5
N.A.
28.7
N.A.
25.8
N.A.
Protein Similarity:
100
97.4
49.7
80.9
N.A.
49.9
45.5
N.A.
N.A.
50
45.9
49.5
N.A.
48.4
N.A.
45.2
N.A.
P-Site Identity:
100
93.3
40
66.6
N.A.
40
13.3
N.A.
N.A.
40
6.6
20
N.A.
13.3
N.A.
13.3
N.A.
P-Site Similarity:
100
100
80
80
N.A.
80
33.3
N.A.
N.A.
80
26.6
66.6
N.A.
46.6
N.A.
46.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
28
0
0
0
55
19
0
0
19
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
19
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
64
0
0
0
28
0
0
0
10
0
0
37
28
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
28
0
0
0
19
73
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
100
10
0
0
0
% H
% Ile:
19
0
19
37
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
46
0
10
0
19
0
0
0
0
10
% K
% Leu:
0
0
19
28
0
0
73
0
10
0
0
0
0
0
0
% L
% Met:
0
0
0
19
0
0
28
0
0
0
0
0
0
0
0
% M
% Asn:
37
0
0
0
10
0
0
0
0
0
0
10
10
0
73
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
10
0
0
0
0
0
55
19
0
0
% Q
% Arg:
0
19
0
0
0
0
0
19
0
0
0
0
0
0
0
% R
% Ser:
28
0
0
0
37
19
0
19
10
0
0
0
0
0
0
% S
% Thr:
19
0
10
0
28
0
0
0
0
10
0
19
0
0
0
% T
% Val:
0
0
55
19
0
0
0
0
0
46
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
55
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _