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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SHISA7
All Species:
1.82
Human Site:
T249
Identified Species:
5.71
UniProt:
A6NL88
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A6NL88
NP_001138648.1
538
56214
T249
R
A
R
S
S
S
L
T
P
G
I
G
G
P
D
Chimpanzee
Pan troglodytes
XP_001153258
296
34049
F20
D
R
N
S
R
G
R
F
L
E
P
H
T
M
T
Rhesus Macaque
Macaca mulatta
XP_001089455
295
32277
Y19
P
D
N
L
H
H
N
Y
L
H
L
N
V
N
S
Dog
Lupus familis
XP_854041
413
43938
L136
P
P
R
T
P
K
N
L
Y
N
T
V
K
P
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8C3Q5
558
58315
L269
A
P
R
T
P
K
N
L
Y
N
T
M
K
P
S
Rat
Rattus norvegicus
NP_001138647
558
58336
L269
A
P
R
T
P
K
N
L
Y
N
T
M
K
P
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521436
295
30551
L19
A
S
A
A
L
A
V
L
A
G
G
R
P
A
N
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001332022
632
69355
S284
D
N
R
T
G
K
H
S
F
G
Q
T
G
S
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
24.1
51.1
63
N.A.
89.9
89.9
N.A.
34.7
N.A.
N.A.
31.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
35.1
53.1
66.7
N.A.
91.9
92.1
N.A.
41.6
N.A.
N.A.
41.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
0
13.3
N.A.
13.3
13.3
N.A.
6.6
N.A.
N.A.
20
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
6.6
6.6
20
N.A.
20
20
N.A.
40
N.A.
N.A.
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
38
13
13
13
0
13
0
0
13
0
0
0
0
13
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
25
13
0
0
0
0
0
0
0
0
0
0
0
0
13
% D
% Glu:
0
0
0
0
0
0
0
0
0
13
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
13
13
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
13
13
0
0
0
38
13
13
25
0
0
% G
% His:
0
0
0
0
13
13
13
0
0
13
0
13
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
13
0
0
0
0
% I
% Lys:
0
0
0
0
0
50
0
0
0
0
0
0
38
0
0
% K
% Leu:
0
0
0
13
13
0
13
50
25
0
13
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
25
0
13
0
% M
% Asn:
0
13
25
0
0
0
50
0
0
38
0
13
0
13
13
% N
% Pro:
25
38
0
0
38
0
0
0
13
0
13
0
13
50
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
13
0
0
0
0
% Q
% Arg:
13
13
63
0
13
0
13
0
0
0
0
13
0
0
0
% R
% Ser:
0
13
0
25
13
13
0
13
0
0
0
0
0
13
63
% S
% Thr:
0
0
0
50
0
0
0
13
0
0
38
13
13
0
13
% T
% Val:
0
0
0
0
0
0
13
0
0
0
0
13
13
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
13
38
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _