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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
All Species:
10.3
Human Site:
S218
Identified Species:
22.67
UniProt:
A6NK25
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A6NK25
NP_958802
285
31668
S218
D
I
T
A
N
L
D
S
P
R
V
T
M
A
Q
Chimpanzee
Pan troglodytes
XP_001174997
436
46878
S351
D
I
T
A
N
L
D
S
P
R
V
T
V
A
Q
Rhesus Macaque
Macaca mulatta
XP_001100213
330
36755
S218
D
I
T
A
N
L
D
S
P
R
V
T
V
A
Q
Dog
Lupus familis
XP_852896
319
34952
E243
A
D
V
L
Y
C
P
E
T
V
L
S
L
V
R
Cat
Felis silvestris
Mouse
Mus musculus
Q3UZW7
335
36922
S219
T
P
I
D
A
G
S
S
K
V
T
V
A
Q
L
Rat
Rattus norvegicus
NP_001100445
335
36972
P219
T
P
I
D
S
G
S
P
K
V
T
V
A
Q
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001025798
338
37684
P228
E
G
K
E
Y
Q
Q
P
K
L
V
V
A
E
L
Frog
Xenopus laevis
NP_001090098
316
35802
V227
E
A
A
N
P
E
S
V
Q
V
S
V
M
E
L
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_573368
319
35261
A251
Q
F
D
A
L
L
G
A
M
D
Y
L
Y
S
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P30643
371
42049
T248
S
A
N
N
N
Q
A
T
V
R
S
L
N
W
C
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P47163
339
38978
R230
E
P
D
I
K
L
Q
R
L
W
W
G
S
D
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
55
77.8
59.8
N.A.
61.4
60.9
N.A.
N.A.
46.4
45.2
N.A.
N.A.
22.2
N.A.
20.7
N.A.
Protein Similarity:
100
58.7
81.2
68.6
N.A.
68.9
68.3
N.A.
N.A.
58.2
61
N.A.
N.A.
40.4
N.A.
39
N.A.
P-Site Identity:
100
93.3
93.3
0
N.A.
6.6
0
N.A.
N.A.
6.6
6.6
N.A.
N.A.
13.3
N.A.
13.3
N.A.
P-Site Similarity:
100
100
100
26.6
N.A.
6.6
6.6
N.A.
N.A.
13.3
13.3
N.A.
N.A.
33.3
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
23.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
38.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
19
10
37
10
0
10
10
0
0
0
0
28
28
0
% A
% Cys:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
10
% C
% Asp:
28
10
19
19
0
0
28
0
0
10
0
0
0
10
0
% D
% Glu:
28
0
0
10
0
10
0
10
0
0
0
0
0
19
0
% E
% Phe:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
10
0
0
0
19
10
0
0
0
0
10
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
28
19
10
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
10
0
10
0
0
0
28
0
0
0
0
0
0
% K
% Leu:
0
0
0
10
10
46
0
0
10
10
10
19
10
0
37
% L
% Met:
0
0
0
0
0
0
0
0
10
0
0
0
19
0
0
% M
% Asn:
0
0
10
19
37
0
0
0
0
0
0
0
10
0
0
% N
% Pro:
0
28
0
0
10
0
10
19
28
0
0
0
0
0
0
% P
% Gln:
10
0
0
0
0
19
19
0
10
0
0
0
0
19
28
% Q
% Arg:
0
0
0
0
0
0
0
10
0
37
0
0
0
0
28
% R
% Ser:
10
0
0
0
10
0
28
37
0
0
19
10
10
10
0
% S
% Thr:
19
0
28
0
0
0
0
10
10
0
19
28
0
0
0
% T
% Val:
0
0
10
0
0
0
0
10
10
37
37
37
19
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
10
10
0
0
10
0
% W
% Tyr:
0
0
0
0
19
0
0
0
0
0
10
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _