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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMCHD1
All Species:
21.52
Human Site:
S741
Identified Species:
52.59
UniProt:
A6NHR9
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A6NHR9
NP_056110.2
2005
226374
S741
P
G
T
S
H
G
G
S
K
K
L
L
V
E
L
Chimpanzee
Pan troglodytes
XP_512045
2005
226402
S741
P
G
T
S
H
G
G
S
K
K
L
L
V
E
L
Rhesus Macaque
Macaca mulatta
XP_001086253
1365
152814
P256
A
D
T
Y
A
G
R
P
L
P
S
K
A
I
K
Dog
Lupus familis
XP_547657
2003
226563
S746
P
G
T
S
H
G
G
S
K
K
L
L
V
E
L
Cat
Felis silvestris
Mouse
Mus musculus
Q6P5D8
2007
225630
S741
P
G
T
S
H
G
G
S
K
K
L
L
V
E
L
Rat
Rattus norvegicus
XP_001056555
2006
226030
S741
P
G
T
S
H
G
G
S
K
K
L
L
V
E
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508602
1277
142834
Q168
N
G
T
A
F
P
F
Q
V
E
V
L
D
E
A
Chicken
Gallus gallus
XP_419144
1794
203200
L671
L
K
V
T
L
P
G
L
K
E
D
T
K
I
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_699397
1203
136319
T94
G
K
T
L
Q
L
M
T
S
V
N
Q
E
L
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788327
2012
226821
S733
L
P
G
A
Q
H
N
S
K
K
L
M
V
E
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
66.6
91.3
N.A.
86.5
88
N.A.
47.2
66.5
N.A.
31.8
N.A.
N.A.
N.A.
N.A.
44.8
Protein Similarity:
100
99.7
67.2
95
N.A.
93.5
94.2
N.A.
54.4
77.1
N.A.
44
N.A.
N.A.
N.A.
N.A.
64.2
P-Site Identity:
100
100
13.3
100
N.A.
100
100
N.A.
26.6
20
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
40
P-Site Similarity:
100
100
13.3
100
N.A.
100
100
N.A.
46.6
33.3
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
20
10
0
0
0
0
0
0
0
10
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
0
0
0
0
0
0
10
0
10
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
20
0
0
10
70
0
% E
% Phe:
0
0
0
0
10
0
10
0
0
0
0
0
0
0
0
% F
% Gly:
10
60
10
0
0
60
60
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
50
10
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
20
0
% I
% Lys:
0
20
0
0
0
0
0
0
70
60
0
10
10
0
10
% K
% Leu:
20
0
0
10
10
10
0
10
10
0
60
60
0
10
60
% L
% Met:
0
0
0
0
0
0
10
0
0
0
0
10
0
0
10
% M
% Asn:
10
0
0
0
0
0
10
0
0
0
10
0
0
0
0
% N
% Pro:
50
10
0
0
0
20
0
10
0
10
0
0
0
0
10
% P
% Gln:
0
0
0
0
20
0
0
10
0
0
0
10
0
0
0
% Q
% Arg:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
50
0
0
0
60
10
0
10
0
0
0
0
% S
% Thr:
0
0
80
10
0
0
0
10
0
0
0
10
0
0
0
% T
% Val:
0
0
10
0
0
0
0
0
10
10
10
0
60
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _