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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SMCHD1 All Species: 10
Human Site: S365 Identified Species: 24.44
UniProt: A6NHR9 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A6NHR9 NP_056110.2 2005 226374 S365 K G N E I R T S K E V E P F N
Chimpanzee Pan troglodytes XP_512045 2005 226402 S365 K G N E I R T S K E V E P F N
Rhesus Macaque Macaca mulatta XP_001086253 1365 152814
Dog Lupus familis XP_547657 2003 226563 S370 K G N E K H T S K E V G P F N
Cat Felis silvestris
Mouse Mus musculus Q6P5D8 2007 225630 A365 K G N E I S T A K A I G P F N
Rat Rattus norvegicus XP_001056555 2006 226030 A365 K G N E I S T A K D V G P F N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508602 1277 142834
Chicken Gallus gallus XP_419144 1794 203200 P348 I T T R T D L P S K R M Q S P
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_699397 1203 136319
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_788327 2012 226821 S352 Q G N Q S H L S N S M Y R T P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 66.6 91.3 N.A. 86.5 88 N.A. 47.2 66.5 N.A. 31.8 N.A. N.A. N.A. N.A. 44.8
Protein Similarity: 100 99.7 67.2 95 N.A. 93.5 94.2 N.A. 54.4 77.1 N.A. 44 N.A. N.A. N.A. N.A. 64.2
P-Site Identity: 100 100 0 80 N.A. 66.6 73.3 N.A. 0 0 N.A. 0 N.A. N.A. N.A. N.A. 20
P-Site Similarity: 100 100 0 80 N.A. 80 86.6 N.A. 0 6.6 N.A. 0 N.A. N.A. N.A. N.A. 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 20 0 10 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 10 0 0 0 10 0 0 0 0 0 % D
% Glu: 0 0 0 50 0 0 0 0 0 30 0 20 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 50 0 % F
% Gly: 0 60 0 0 0 0 0 0 0 0 0 30 0 0 0 % G
% His: 0 0 0 0 0 20 0 0 0 0 0 0 0 0 0 % H
% Ile: 10 0 0 0 40 0 0 0 0 0 10 0 0 0 0 % I
% Lys: 50 0 0 0 10 0 0 0 50 10 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 20 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 10 10 0 0 0 % M
% Asn: 0 0 60 0 0 0 0 0 10 0 0 0 0 0 50 % N
% Pro: 0 0 0 0 0 0 0 10 0 0 0 0 50 0 20 % P
% Gln: 10 0 0 10 0 0 0 0 0 0 0 0 10 0 0 % Q
% Arg: 0 0 0 10 0 20 0 0 0 0 10 0 10 0 0 % R
% Ser: 0 0 0 0 10 20 0 40 10 10 0 0 0 10 0 % S
% Thr: 0 10 10 0 10 0 50 0 0 0 0 0 0 10 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 40 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _