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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMCHD1
All Species:
13.33
Human Site:
S1974
Identified Species:
32.59
UniProt:
A6NHR9
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A6NHR9
NP_056110.2
2005
226374
S1974
C
N
D
S
L
R
H
S
P
K
V
E
T
T
D
Chimpanzee
Pan troglodytes
XP_512045
2005
226402
S1974
C
N
D
S
L
R
H
S
P
K
V
E
T
T
D
Rhesus Macaque
Macaca mulatta
XP_001086253
1365
152814
R1335
A
P
P
M
D
K
L
R
G
M
V
F
G
A
P
Dog
Lupus familis
XP_547657
2003
226563
T1969
Q
K
L
G
M
T
P
T
R
K
C
N
D
S
L
Cat
Felis silvestris
Mouse
Mus musculus
Q6P5D8
2007
225630
S1975
C
N
E
S
L
C
H
S
P
K
I
E
V
T
E
Rat
Rattus norvegicus
XP_001056555
2006
226030
S1974
C
S
D
S
L
C
L
S
P
K
I
E
V
T
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508602
1277
142834
W1247
P
D
V
S
P
K
A
W
R
S
S
G
T
S
P
Chicken
Gallus gallus
XP_419144
1794
203200
V1754
K
R
M
R
K
E
T
V
K
K
L
Y
S
S
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_699397
1203
136319
N1173
E
V
M
D
Q
Y
G
N
K
T
D
R
L
D
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788327
2012
226821
A1965
I
N
Q
K
L
K
L
A
E
A
S
S
T
D
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
66.6
91.3
N.A.
86.5
88
N.A.
47.2
66.5
N.A.
31.8
N.A.
N.A.
N.A.
N.A.
44.8
Protein Similarity:
100
99.7
67.2
95
N.A.
93.5
94.2
N.A.
54.4
77.1
N.A.
44
N.A.
N.A.
N.A.
N.A.
64.2
P-Site Identity:
100
100
6.6
6.6
N.A.
66.6
60
N.A.
13.3
6.6
N.A.
0
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
100
100
13.3
26.6
N.A.
86.6
80
N.A.
33.3
33.3
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
0
10
10
0
10
0
0
0
10
10
% A
% Cys:
40
0
0
0
0
20
0
0
0
0
10
0
0
0
0
% C
% Asp:
0
10
30
10
10
0
0
0
0
0
10
0
10
20
20
% D
% Glu:
10
0
10
0
0
10
0
0
10
0
0
40
0
0
30
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% F
% Gly:
0
0
0
10
0
0
10
0
10
0
0
10
10
0
0
% G
% His:
0
0
0
0
0
0
30
0
0
0
0
0
0
0
10
% H
% Ile:
10
0
0
0
0
0
0
0
0
0
20
0
0
0
0
% I
% Lys:
10
10
0
10
10
30
0
0
20
60
0
0
0
0
0
% K
% Leu:
0
0
10
0
50
0
30
0
0
0
10
0
10
0
10
% L
% Met:
0
0
20
10
10
0
0
0
0
10
0
0
0
0
0
% M
% Asn:
0
40
0
0
0
0
0
10
0
0
0
10
0
0
0
% N
% Pro:
10
10
10
0
10
0
10
0
40
0
0
0
0
0
20
% P
% Gln:
10
0
10
0
10
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
10
0
10
0
20
0
10
20
0
0
10
0
0
0
% R
% Ser:
0
10
0
50
0
0
0
40
0
10
20
10
10
30
0
% S
% Thr:
0
0
0
0
0
10
10
10
0
10
0
0
40
40
0
% T
% Val:
0
10
10
0
0
0
0
10
0
0
30
0
20
0
0
% V
% Trp:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
10
0
0
0
0
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _