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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMCHD1
All Species:
12.12
Human Site:
S1418
Identified Species:
29.63
UniProt:
A6NHR9
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A6NHR9
NP_056110.2
2005
226374
S1418
S
M
K
M
W
K
L
S
T
S
G
N
R
P
P
Chimpanzee
Pan troglodytes
XP_512045
2005
226402
C1418
S
M
K
M
W
K
L
C
T
S
G
N
R
P
P
Rhesus Macaque
Macaca mulatta
XP_001086253
1365
152814
N854
D
S
I
I
K
N
I
N
P
A
R
I
S
M
K
Dog
Lupus familis
XP_547657
2003
226563
S1423
S
M
K
M
W
Q
L
S
N
S
G
N
R
P
P
Cat
Felis silvestris
Mouse
Mus musculus
Q6P5D8
2007
225630
S1419
S
M
K
M
W
K
L
S
S
G
M
S
R
P
P
Rat
Rattus norvegicus
XP_001056555
2006
226030
S1418
S
M
K
M
W
K
L
S
S
G
M
S
R
P
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508602
1277
142834
N766
K
S
S
I
E
E
D
N
E
T
P
L
F
Q
G
Chicken
Gallus gallus
XP_419144
1794
203200
R1270
N
V
R
T
I
T
S
R
T
L
V
K
D
L
C
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_699397
1203
136319
W692
T
W
P
E
G
N
A
W
E
D
K
D
A
Y
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788327
2012
226821
A1425
S
M
R
L
W
K
S
A
T
N
D
Q
H
S
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
66.6
91.3
N.A.
86.5
88
N.A.
47.2
66.5
N.A.
31.8
N.A.
N.A.
N.A.
N.A.
44.8
Protein Similarity:
100
99.7
67.2
95
N.A.
93.5
94.2
N.A.
54.4
77.1
N.A.
44
N.A.
N.A.
N.A.
N.A.
64.2
P-Site Identity:
100
93.3
0
86.6
N.A.
73.3
73.3
N.A.
0
6.6
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
33.3
P-Site Similarity:
100
93.3
26.6
93.3
N.A.
86.6
86.6
N.A.
26.6
26.6
N.A.
20
N.A.
N.A.
N.A.
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
10
10
0
10
0
0
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
10
% C
% Asp:
10
0
0
0
0
0
10
0
0
10
10
10
10
0
0
% D
% Glu:
0
0
0
10
10
10
0
0
20
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% F
% Gly:
0
0
0
0
10
0
0
0
0
20
30
0
0
0
20
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% H
% Ile:
0
0
10
20
10
0
10
0
0
0
0
10
0
0
0
% I
% Lys:
10
0
50
0
10
50
0
0
0
0
10
10
0
0
10
% K
% Leu:
0
0
0
10
0
0
50
0
0
10
0
10
0
10
0
% L
% Met:
0
60
0
50
0
0
0
0
0
0
20
0
0
10
0
% M
% Asn:
10
0
0
0
0
20
0
20
10
10
0
30
0
0
0
% N
% Pro:
0
0
10
0
0
0
0
0
10
0
10
0
0
50
60
% P
% Gln:
0
0
0
0
0
10
0
0
0
0
0
10
0
10
0
% Q
% Arg:
0
0
20
0
0
0
0
10
0
0
10
0
50
0
0
% R
% Ser:
60
20
10
0
0
0
20
40
20
30
0
20
10
10
0
% S
% Thr:
10
0
0
10
0
10
0
0
40
10
0
0
0
0
0
% T
% Val:
0
10
0
0
0
0
0
0
0
0
10
0
0
0
0
% V
% Trp:
0
10
0
0
60
0
0
10
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _