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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DCAF8L1 All Species: 4.24
Human Site: Y539 Identified Species: 9.33
UniProt: A6NGE4 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A6NGE4 NP_001017930.1 600 67373 Y539 R D E D N L N Y T D S F D N R
Chimpanzee Pan troglodytes XP_528917 668 74962 Y550 R D E D N L N Y T D S F D N H
Rhesus Macaque Macaca mulatta XP_001093859 611 68308 H551 R D E D N L H H I D P F D N H
Dog Lupus familis XP_536129 596 66580 H535 R D E D S L H H T D L F D S H
Cat Felis silvestris
Mouse Mus musculus Q8N7N5 591 66013 H530 R D E D S L H H T D L F D S H
Rat Rattus norvegicus Q5U2M6 591 66137 H530 R D E D S L H H T D L F D S H
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis Q6NRH1 601 67089 H539 R D E D S L H H T D L F D N H
Zebra Danio Brachydanio rerio XP_001346262 607 66784 H548 R D E D N V R H G D Q Y D T Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_647657 748 83317 N671 S I D L D I N N F Q Y F I R G
Honey Bee Apis mellifera XP_392352 669 75650 E598 R A Q E T T T E S D A F D R R
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_785904 416 46675 L379 L R F L M A H L R H R A R R Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 87.2 89.5 67.1 N.A. 65.1 65.8 N.A. N.A. N.A. 60.7 51.7 N.A. 29.1 33.6 N.A. 38.1
Protein Similarity: 100 88.1 92.6 78 N.A. 78 77.8 N.A. N.A. N.A. 73.5 67.3 N.A. 45.9 53.8 N.A. 50.1
P-Site Identity: 100 93.3 66.6 60 N.A. 60 60 N.A. N.A. N.A. 66.6 46.6 N.A. 13.3 33.3 N.A. 0
P-Site Similarity: 100 93.3 80 86.6 N.A. 86.6 86.6 N.A. N.A. N.A. 86.6 73.3 N.A. 33.3 60 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 0 0 0 10 0 0 0 0 10 10 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 73 10 73 10 0 0 0 0 82 0 0 82 0 0 % D
% Glu: 0 0 73 10 0 0 0 10 0 0 0 0 0 0 0 % E
% Phe: 0 0 10 0 0 0 0 0 10 0 0 82 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 10 % G
% His: 0 0 0 0 0 0 55 55 0 10 0 0 0 0 55 % H
% Ile: 0 10 0 0 0 10 0 0 10 0 0 0 10 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 10 0 0 19 0 64 0 10 0 0 37 0 0 0 0 % L
% Met: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 37 0 28 10 0 0 0 0 0 37 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % P
% Gln: 0 0 10 0 0 0 0 0 0 10 10 0 0 0 19 % Q
% Arg: 82 10 0 0 0 0 10 0 10 0 10 0 10 28 19 % R
% Ser: 10 0 0 0 37 0 0 0 10 0 19 0 0 28 0 % S
% Thr: 0 0 0 0 10 10 10 0 55 0 0 0 0 10 0 % T
% Val: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 19 0 0 10 10 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _