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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DCAF8L1
All Species:
16.97
Human Site:
S584
Identified Species:
37.33
UniProt:
A6NGE4
Number Species:
10
Phosphosite Substitution
Charge Score:
0.3
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A6NGE4
NP_001017930.1
600
67373
S584
L
D
E
S
S
S
T
S
D
T
S
E
E
E
G
Chimpanzee
Pan troglodytes
XP_528917
668
74962
S595
L
D
E
S
S
S
T
S
D
T
S
E
G
G
R
Rhesus Macaque
Macaca mulatta
XP_001093859
611
68308
S595
L
D
E
S
S
S
T
S
D
T
S
E
E
E
G
Dog
Lupus familis
XP_536129
596
66580
D580
D
E
S
P
S
S
S
D
T
S
D
E
E
E
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8N7N5
591
66013
D575
D
E
S
P
S
S
S
D
T
S
D
E
E
E
G
Rat
Rattus norvegicus
Q5U2M6
591
66137
D575
D
E
S
P
S
S
S
D
T
S
D
E
E
E
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6NRH1
601
67089
S585
D
S
P
S
S
S
D
S
S
D
D
D
E
D
G
Zebra Danio
Brachydanio rerio
XP_001346262
607
66784
S591
E
S
W
S
S
P
E
S
S
D
E
E
D
G
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_647657
748
83317
S726
H
R
R
N
S
N
S
S
D
D
T
N
D
E
G
Honey Bee
Apis mellifera
XP_392352
669
75650
H651
I
L
E
D
S
S
D
H
S
D
S
Q
S
E
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785904
416
46675
T401
D
S
S
D
S
D
E
T
S
E
S
S
E
D
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87.2
89.5
67.1
N.A.
65.1
65.8
N.A.
N.A.
N.A.
60.7
51.7
N.A.
29.1
33.6
N.A.
38.1
Protein Similarity:
100
88.1
92.6
78
N.A.
78
77.8
N.A.
N.A.
N.A.
73.5
67.3
N.A.
45.9
53.8
N.A.
50.1
P-Site Identity:
100
80
100
40
N.A.
40
40
N.A.
N.A.
N.A.
40
33.3
N.A.
33.3
40
N.A.
20
P-Site Similarity:
100
80
100
60
N.A.
60
60
N.A.
N.A.
N.A.
53.3
40
N.A.
66.6
53.3
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
46
28
0
19
0
10
19
28
37
37
37
10
19
19
0
% D
% Glu:
10
28
37
0
0
0
19
0
0
10
10
64
64
64
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
10
19
82
% G
% His:
10
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% H
% Ile:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
28
10
0
0
0
0
0
0
0
0
0
0
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
10
0
10
0
0
0
0
0
10
0
0
0
% N
% Pro:
0
0
10
28
0
10
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% Q
% Arg:
0
10
10
0
0
0
0
0
0
0
0
0
0
0
10
% R
% Ser:
0
28
37
46
100
73
37
55
37
28
46
10
10
0
0
% S
% Thr:
0
0
0
0
0
0
28
10
28
28
10
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _