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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DCAF8L1 All Species: 28.48
Human Site: S168 Identified Species: 62.67
UniProt: A6NGE4 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A6NGE4 NP_001017930.1 600 67373 S168 L R Q R Q L G S S A R F V Y E
Chimpanzee Pan troglodytes XP_528917 668 74962 S179 L R Q R Q L G S S A R F V Y E
Rhesus Macaque Macaca mulatta XP_001093859 611 68308 S180 L R Q R Q L G S S A R F V Y E
Dog Lupus familis XP_536129 596 66580 S164 L R E R E L G S S A R F V Y E
Cat Felis silvestris
Mouse Mus musculus Q8N7N5 591 66013 S159 L R E R E L G S S A R F V Y E
Rat Rattus norvegicus Q5U2M6 591 66137 S159 L R E R E L G S S A R F V Y E
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis Q6NRH1 601 67089 S168 L R Q R Q M G S S T R F I Y E
Zebra Danio Brachydanio rerio XP_001346262 607 66784 D177 R A R E I G R D S Q Q F V R K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_647657 748 83317 S298 D W R G G H T S A S S F G Q G
Honey Bee Apis mellifera XP_392352 669 75650 I238 L L H R E I G I N P S F Q R R
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_785904 416 46675 D41 L L A S G S D D L E I V L W D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 87.2 89.5 67.1 N.A. 65.1 65.8 N.A. N.A. N.A. 60.7 51.7 N.A. 29.1 33.6 N.A. 38.1
Protein Similarity: 100 88.1 92.6 78 N.A. 78 77.8 N.A. N.A. N.A. 73.5 67.3 N.A. 45.9 53.8 N.A. 50.1
P-Site Identity: 100 100 100 86.6 N.A. 86.6 86.6 N.A. N.A. N.A. 80 20 N.A. 13.3 26.6 N.A. 6.6
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. N.A. 93.3 40 N.A. 33.3 46.6 N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 10 0 0 0 0 0 10 55 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 0 0 0 0 0 10 19 0 0 0 0 0 0 10 % D
% Glu: 0 0 28 10 37 0 0 0 0 10 0 0 0 0 64 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 91 0 0 0 % F
% Gly: 0 0 0 10 19 10 73 0 0 0 0 0 10 0 10 % G
% His: 0 0 10 0 0 10 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 10 10 0 10 0 0 10 0 10 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % K
% Leu: 82 19 0 0 0 55 0 0 10 0 0 0 10 0 0 % L
% Met: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % P
% Gln: 0 0 37 0 37 0 0 0 0 10 10 0 10 10 0 % Q
% Arg: 10 64 19 73 0 0 10 0 0 0 64 0 0 19 10 % R
% Ser: 0 0 0 10 0 10 0 73 73 10 19 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 10 0 0 10 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 10 64 0 0 % V
% Trp: 0 10 0 0 0 0 0 0 0 0 0 0 0 10 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 64 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _